Apolipoproteins L

A family of apolipoproteins occurring in humans that are structurally similar to B-CELL LEUKEMIA 2 FAMILY PROTEINS. In addition to their roles in cholesterol and lipid transport, they are expressed by MYELOID CELLS and ENDOTHELIAL CELLS during INFLAMMATION and may function to promote CELL DEATH.

Also Known As:

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Pays, Etienne: 1 article (01/2021)
2.	Malik, Harmit S: 1 article (05/2009)
3.	Smith, Eric E: 1 article (05/2009)
4.	Arai, Heii: 1 article (04/2002)
5.	Baba, Hajime: 1 article (04/2002)
6.	Bahn, Sabine: 1 article (04/2002)
7.	Emson, Piers C: 1 article (04/2002)
8.	Faull, Richard L M: 1 article (04/2002)
9.	Iritani, Shuji: 1 article (04/2002)
10.	Jones, Peter B: 1 article (04/2002)

Related Diseases

1.	Virus Diseases (Viral Diseases) 01/01/2021 - "The function of apolipoproteins L (APOLs): relevance for kidney disease, neurotransmission disorders, cancer and viral infection."
2.	Sudden Infant Death (SID) 05/01/2009 - "We predict that APOL genes are antagonized by pathogens by at least two distinct mechanisms: SID antagonists, which include SRA, that interact with the SID of various APOL proteins, and MAD antagonists that interact with the MAD hinge base of APOL6. "
3.	Schizophrenia (Dementia Praecox) 04/02/2002 - "Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22."
4.	Neoplasms (Cancer) 01/01/2021 - "The function of apolipoproteins L (APOLs): relevance for kidney disease, neurotransmission disorders, cancer and viral infection."
5.	Kidney Diseases (Kidney Disease) 01/01/2021 - "The function of apolipoproteins L (APOLs): relevance for kidney disease, neurotransmission disorders, cancer and viral infection."