Apolipoproteins M

Apolipoproteins and lipocalins that occur in HIGH-DENSITY LIPOPROTEINS. They bind or transport lipids in the blood including sphingosine-1-phosphate, MYRISTIC ACID; STEARIC ACIDS; and ALL-TRANS-RETINOIC ACID.

Also Known As:

Networked: 126 relevant articles (2 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Xu, Ning: 22 articles (02/2022 - 05/2005)
2.	Luo, Guanghua: 21 articles (02/2022 - 05/2005)
3.	Dahlbäck, Björn: 17 articles (01/2020 - 06/2006)
4.	Zhang, Xiaoying: 16 articles (12/2020 - 05/2005)
5.	Zhang, Jun: 13 articles (12/2020 - 12/2009)
6.	Christoffersen, Christina: 12 articles (07/2022 - 01/2008)
7.	Zheng, Lu: 12 articles (01/2021 - 12/2009)
8.	Wei, Jiang: 9 articles (02/2022 - 12/2009)
9.	Mu, Qinfeng: 9 articles (01/2021 - 12/2009)
10.	Nielsen, Lars Bo: 9 articles (01/2018 - 01/2008)

Related Diseases

1.	Atherosclerosis 10/01/2017 - "Effects of apolipoprotein M in uremic atherosclerosis." 07/01/2013 - "The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. " 03/01/2012 - "Overexpression of HDL-associated apolipoprotein M (apoM) protects mice against atherosclerosis through a not yet clarified mechanism. " 05/13/2011 - "Apolipoprotein M (apoM) has been recently shown to play a role in the maturation of HDL in plasma and to protect from atherosclerosis. " 02/01/2010 - "Characteristics of apolipoprotein M and its relation to atherosclerosis and diabetes."
2.	Insulin Resistance 11/01/2014 - "The association between apolipoprotein M and insulin resistance varies with country of birth." 01/01/2020 - "Previous clinical studies have suggested that apolipoprotein M (apoM) is involved in glucose metabolism and plays a causative role in insulin sensitivity. " 01/01/2020 - "Insulin Resistance in Apolipoprotein M Knockout Mice is Mediated by the Protein Kinase Akt Signaling Pathway." 01/01/2014 - "Intralipid decreases apolipoprotein M levels and insulin sensitivity in rats." 01/01/2020 - "Protection Against Insulin Resistance by Apolipoprotein M/Sphingosine-1-Phosphate."
3.	Type 2 Diabetes Mellitus (MODY) 01/01/2020 - "Recent studies have discovered a role of apolipoprotein M (apoM) in energy metabolism, and observational analyses in humans suggest an association with type 2 diabetes. " 01/01/2021 - "Apolipoprotein M (ApoM) may have a role in the susceptibility of type 2 diabetes mellitus (T2DM). " 01/01/2021 - "Apolipoprotein M Gene Polymorphism Rs805297 (C-1065A): Association With Type 2 Diabetes Mellitus and Related Microvascular Complications in South Egypt." 01/01/2020 - "Apolipoprotein M and Risk of Type 2 Diabetes." 03/01/2017 - "Apolipoprotein M (apoM) concentrations were decreased in type 2 diabetes mellitus (T2DM). "
4.	Coronary Artery Disease (Coronary Atherosclerosis) 01/01/2014 - "The present study investigated the correlation among genetic polymorphisms of the proximal promoter region of apolipoprotein M (apoM) gene, the polymorphisms in relation to apoM expressions and the susceptibility to coronary artery diseases (CAD) in a Han Chinese population. " 01/02/2016 - "The present meta-analysis aimed to summarize the inconsistent findings on the association of apolipoprotein M gene (ApoM) rs805296 polymorphism with the risk of coronary artery disease (CAD), and to obtain a more authentic result about this topic. " 04/01/2014 - "To investigate the association between genetic polymorphisms of proximal promoter region of apolipoprotein M (apoM) gene and susceptibility of coronary artery diseases (CAD) in Han Chinese population. " 04/01/2014 - "[Association between a new SNP in proximal promoter region of apolipoprotein M and susceptibility of coronary artery diseases in Han Chinese population]." 01/01/2014 - "Decreased activities of apolipoprotein m promoter are associated with the susceptibility to coronary artery diseases."
5.	Inflammation (Inflammations) 10/01/2021 - "Apolipoprotein M and its impact on endothelial dysfunction and inflammation in the cardiovascular system." 07/01/2008 - "Infection and inflammation decrease apolipoprotein M expression." 01/01/2007 - "Apolipoprotein M likely extends its anti-atherogenesis via anti-inflammation." 04/01/2019 - "Studies have shown that apolipoprotein M (apoM), the main carrier of sphingosine-1-phosphate (S1P), is closely related to lipid metabolism and inflammation. " 12/02/2019 - "Apolipoprotein M and sphingosine-1-phosphate complex alleviates TNF-α-induced endothelial cell injury and inflammation through PI3K/AKT signaling pathway."

Related Drugs and Biologics

1.	Sphingosine
2.	Phosphates (Orthophosphate)
3.	Apoproteins
4.	Messenger RNA (mRNA)
5.	HDL Lipoproteins
6.	sphingosine 1-phosphate (sphingosine-1-phosphate)
7.	Biomarkers (Surrogate Marker)
8.	Proteins (Proteins, Gene)
9.	Carrier Proteins (Binding Protein)
10.	Apolipoprotein A-I (Apolipoprotein A1)

Related Therapies and Procedures

1.	Continuous Positive Airway Pressure
2.	Critical Care (Surgical Intensive Care)