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Abuse-Deterrent Formulations

Drug formulations or delivery systems intended to discourage the abuse of CONTROLLED SUBSTANCES. These may include physical barriers to prevent chewing or crushing the drug; chemical barriers that prevent extraction of psychoactive ingredients; agonist-antagonist combinations to reduce euphoria associated with abuse; aversion, where controlled substances are combined with others that will produce an unpleasant effect if the patient manipulates the dosage form or exceeds the recommended dose; delivery systems that are resistant to abuse such as implants; or combinations of these methods.
Also Known As:
Abuse Deterrent Formulation; Abuse Deterrent Formulations; Formulation, Abuse-Deterrent; Formulations, Abuse-Deterrent; Abuse-Deterrent Formulation
Networked: 39 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Taylor, Robert: 4 articles (01/2018 - 01/2012)
2. Cone, Edward J: 3 articles (01/2019 - 05/2016)
3. Pergolizzi, Joseph V: 3 articles (01/2018 - 01/2012)
4. Raffa, Robert B: 3 articles (01/2018 - 01/2012)
5. Dasgupta, Nabarun: 2 articles (01/2021 - 11/2016)
6. Kopecky, Ernest A: 2 articles (01/2018 - 01/2016)
7. LeQuang, Jo Ann: 2 articles (01/2018 - 01/2018)
8. Markman, John: 2 articles (01/2018 - 01/2017)
9. Vaughn, Ben: 2 articles (01/2018 - 01/2016)
10. Bass, Almasa: 2 articles (10/2017 - 01/2015)

Related Diseases

1. Pain (Aches)
2. Low Back Pain (Lumbago)
3. Cancer Pain
4. Opioid-Related Disorders (Opiate Addiction)
5. Substance-Related Disorders (Drug Abuse)

Related Drugs and Biologics

1. Opioid Analgesics (Opioids)
2. Oxycodone (Oxycontin)
3. Naltrexone (ReVia)
4. oxycodone naltrexone combination
5. Analgesics (Analgesic Drugs)
6. Abuse-Deterrent Formulations
7. Prescription Drugs
8. Myristic Acid (Tetradecanoic Acid)
9. Salts
10. Morphine (MS Contin)

Related Therapies and Procedures

1. Therapeutics
2. Pain Management
3. Self Administration (Administration, Self)