Aldo-Keto Reductase Family 1 Member C2
Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8).
Also Known As:
AKR1C2 Protein; Dihydrodiol Dehydrogenase 2; Dihydrodiol Dehydrogenase-Bile Acid Binding Protein; Aldo Keto Reductase Family 1 Member C2; Dihydrodiol Dehydrogenase Bile Acid Binding Protein
Networked: 4
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Qian, Li-Hua:
1 article
(06/2018)
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2. | Ren, Ding-Yu:
1 article
(06/2018)
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3. | Shao, Jie-Bao:
1 article
(06/2018)
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4. | Wang, Yu-Chao:
1 article
(06/2018)
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5. | Xu, Chun-Hua:
1 article
(06/2018)
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6. | Zhang, Qian:
1 article
(06/2018)
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7. | Zhang, Xiu-Wei:
1 article
(06/2018)
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8. | Higashiyama, Shigeki:
1 article
(03/2014)
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9. | Kikugawa, Tadahiko:
1 article
(03/2014)
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10. | Miura, Noriyoshi:
1 article
(03/2014)
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