ATP-binding cassette, subfamily B, protein (P-glycoproteins) that functions in the ATP-dependent secretion of BILE SALTS into the BILE CANALICULI of HEPATOCYTES. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis 2 (see CHOLESTASIS, INTRAHEPATIC).
Also Known As:
ATP Binding Cassette Transporter, Subfamily B, Member 11; ABCB11 Protein; ATP Binding Cassette Subfamily B Member 11; ATP Binding Cassette Transporter, Sub-Family B, Member 11; BSEP Protein; Bile Salt Export Pump