Procedural Pain

02/01/2012 - "FT alone was significantly less effective in relieving repeated procedural pain (P < .002) than sucrose (0.2 mL/kg). "
01/01/2004 - "The purpose of this study was to test the efficacy of treating all procedural pain with sucrose on overall physiological stability. "
03/01/2011 - "There was a 21% overall improvement in the number of infants receiving breastfeeding or sucrose for procedural pain, however, breastfeeding rates remain poorly utilised. "
01/31/2013 - "Sucrose is safe and effective for reducing procedural pain from single events. "
01/20/2010 - "Sucrose is safe and effective for reducing procedural pain from single events. "

12/01/2009 - "Nonpharmacologic analgesic measures were effective for the treatment of procedural pain in term infants. "
01/01/2021 - "We included randomised controlled trials and controlled clinical trials comparing the outcomes of clinical improvement (septic parameters), hospitalisation duration, quality of life, urinary-related symptoms, failure rates, post-procedural pain [measured using a visual analogue scale (VAS)] and analgesics use. "
12/01/2018 - "We performed an analysis of scientific literature from 2001 to 2017, retrieving those clinical trials where SS had been compared with other analgesic treatments during procedural pain in babies. "
04/01/2004 - "Analgesic effect of expressed breast milk in procedural pain in term neonates: a randomized, placebo-controlled, double-blind trial."
07/01/2023 - "Employing an individual's favorite music during episodic or procedural pain might represent a cost effective adjunctive analgesic strategy."

12/01/2005 - "We observed a statistically significant reduction in subject-reported procedural pain in participants pretreated with lidocaine 4% on both sides of the face compared with controls. "
01/01/2020 - "The use of 10% lidocaine spray was more effective in relieving procedural pain and discomfort during nasoenteral catheterization. "
08/01/2005 - "We assessed the procedural and post-procedural pain relief for TRUS biopsy provided by DS, and the combination of DS and lidocaine PPNB compared with lidocaine PPNB alone. "
04/01/2012 - "The data from the four studies evaluated indicate that needle-free lidocaine significantly reduces procedural pain and is a cost-effective alternative to the use of topical lidocaine."
01/01/2022 - "VYC-17.5L was noninferior to control without lidocaine for correcting moderate-to-severe NLFs in Chinese subjects and was superior to control in reducing procedural pain."

05/01/2012 - "Efficacy of an intravenous bolus of morphine 2.5 versus morphine 7.5 mg for procedural pain relief in postoperative cardiothoracic patients in the intensive care unit: a randomised double-blind controlled trial."
01/01/2021 - "Predicting severity of adverse cardiorespiratory effects of morphine in premature infants: a post hoc analysis of Procedural Pain in Premature Infants trial data."
05/01/2009 - "The aim of this study was to examine relationships between cumulative procedural pain (number of skin-breaking procedures from birth to term, adjusted for early illness severity and overall intravenous morphine exposure), and later cognitive, motor abilities and behavior in very preterm infants at 8 and 18 months corrected chronological age (CCA), and further, to evaluate the extent to which parenting factors modulate these relationships over time. "
11/01/2014 - "Post-procedural pain was assessed by the mean amount of self-administered morphine delivered by PCA pump (mL) from 0 to 19 hours in each group. "
11/01/2012 - "Although morphine is frequently administered to treat procedural pain in neonates and young children, little is known about the effects of this drug on developing neural circuitry during the brain growth spurt. "

01/01/2019 - "Our aim was to study these and their relation with a new formulation of fentanyl 5 μg/mL for procedural pain. "
06/01/2012 - "Primary outcome of this study was to evaluate the reduction of procedural pain induced by "heel-lances" in preterm newborns with three different treatment [administration of fentanyl (FE, 1-2 μg/kg), facilitated tucking (FT), sensorial saturation (SS)]. "
01/01/2021 - "The objective was to evaluate the effectiveness and safety of IN fentanyl for procedural pain in preterm infants. "
12/01/2020 - " results indicate that a 100 µg dose of sublingual fentanyl is not beneficial compared to the placebo in the treatment of procedural pain during a colonoscopy."
01/01/2020 - "Large RCTs are required to verify the efficacy and safety of intranasal fentanyl for acute procedural pain in neonates. "

01/01/2019 - "Median (IQR) procedural pain VAS score was 21.5 (16) in ketamine group and 43.5 (29) in control group. "
12/15/2010 - "Use of ketamine in uncontrolled acute and procedural pain."
07/01/2001 - "Ketamine for procedural pain relief in newborn infants."
07/01/2012 - "These findings suggest that concurrent surgery and procedural pain attenuates ketamine-induced neuroapoptosis."
11/01/2019 - "Aim: The aim of this study was to evaluate the therapeutic efficacy and safety profile of orally administered low-dose ketamine for procedural pain management in pediatric cancer patients undergoing lumbar puncture (LP) in a resource-limited hospital setting. "

12/01/2009 - "Skin-to-skin contact and/or oral 25% dextrose for procedural pain relief for term newborn infants."
12/01/2019 - "To study the clinical effect of white noise combined with glucose in reducing the procedural pain of retinopathy screening in preterm infants. "
01/01/2018 - "The aim of this study is to investigate if instilling breast milk (BM) or dextrose water into oral cavity can reduce the procedural pain of heel stick for preterm babies. "
12/01/2021 - "Repeated treatments of neonatal procedural pain with 30% oral dextrose are less energetically demanding. "
12/01/2019 - "White noise combined with glucose can reduce the procedural pain of retionopathy screening and keep vital signs stable in preterm infants."

11/01/2017 - "A randomized controlled study in reducing procedural pain and anxiety using high concentration nitrous oxide."
03/01/2020 - "Findings can potentially develop standardized processes and improve nurse education and accreditation, which may increase the safety, efficacy, and utilization of nitrous oxide for children's procedural pain management."
03/01/2020 - "Improving the Utilisation of Nitrous Oxide in Paediatric Patients to Manage Procedural Pain and Procedural Anxiety."
09/01/2016 - "Occupational exposure to nitrous oxide during procedural pain control in children: a comparison of different inhalation techniques and scavenging systems."
04/01/2008 - "Health aspects among personnel working with nitrous oxide for procedural pain management in children."

01/01/2020 - "A Critical Review on the Relevance of Paracetamol for Procedural Pain Management in Neonates."
01/01/2016 - "Neonatal paracetamol treatment reduces long-term nociceptive behaviour after neonatal procedural pain in rats."
09/01/2010 - "In a setting of open label administration to alleviate (procedural) pain, haemodynamic effects of iv paracetamol in neonates remained modest. "
01/01/2012 - "The results of this review indicate that intravenous acetaminophen (paracetamol) has been used during and following a variety of orthopedic surgical procedures with moderate improvement in post procedural pain, but did not substantially change the need for rescue medications. "
01/01/2016 - "This study, therefore, analyses the short- and long-term consequences of neonatal paracetamol (acetaminophen) treatment on pain behaviour in an experimental rat model of neonatal procedural pain. "

04/01/2022 - "oxygen desaturation), post-procedural pain, and levels of endoscopist and patient satisfaction. "
01/01/2017 - "The aim of the study was to evaluate the efficacy of a fixed 50% nitrous oxide-oxygen mixture compared to placebo to reduce immediate procedural pain and anxiety during LP. "
06/01/2011 - "Equimolar nitrous oxide/oxygen versus placebo for procedural pain in children: a randomized trial."
01/01/2020 - "Administration of fentanyl bolus for procedural pain and sedation was not shown to significantly affect cerebral oxygenation, cerebral tissue oxygen extraction or cardiac output in stable preterm infants."
02/01/2001 - "Inhaled equimolar mixture of nitrous oxide and oxygen prevents procedural pain during renal percutaneous biopsies."

01/07/2022 - "N2O analgesia is safe and effective, resulting in a significant reduction in procedural pain and an improvement in the quality of life of patients and their caregivers."
02/01/2013 - "By 2010 analgesia practices for procedural pain had improved significantly for almost all invasive procedures (p < 0.05), both non-pharmacological and pharmacological methods being adopted by the majority of NICUs (unlike the situation in 2004). "
10/01/2012 - "By 2010, analgesia practices for procedural pain had improved significantly for almost all invasive procedures (p < 0.05), with both non-pharmacological and pharmacological methods being adopted by the majority of NICUs (unlike the situation in 2004). "
09/01/2012 - " Analgesia is safe and effective in reducing the procedural pain associated with newborn circumcision; thus, adequate analgesia should be provided whenever newborn circumcision is performed.Nonpharmacologic"
05/01/2020 - "This study found that despite adequate knowledge about pain perception by neonates, the use of analgesia for procedural pain relief is low among doctors in the NICUs of the Eastern Province of Saudi Arabia. "

06/01/2022 - "Clown therapy seems effective in reducing procedural pain in children, particularly for older age groups, but due to poor methodological quality and the high risk of bias of the studies included, the results obtained should be considered with caution. "
06/01/2022 - "• Clown therapy seems effective in reducing procedural pain and anxiety in children. "
01/01/2015 - "Numerous benefits of its use have been reported related to mortality, physiological (thermoregulation, cardiorespiratory stability), behavioral (sleep, breastfeeding duration, and degree of exclusivity) domains, as an effective therapy to relieve procedural pain, and improved neurodevelopment. "
01/01/2017 - "The availability of a safe and effective pharmacological therapy to reduce procedural pain in preterm infants is limited. "
01/01/2022 - "Evidence-Based Nursing Practices for the Prevention of Newborn Procedural Pain in Neonatal Intensive Therapy-An Exploratory Study."

01/01/2023 - "Clinical hypnosis has emerged as a potentially beneficial treatment for children's procedural pain and distress due to evidence of effectiveness and potential superiority to other psychological interventions. "
06/01/2023 - "This study investigated the efficacy of virtually augmented self-hypnosis as an adjunctive non-pharmacological method for procedural pain and anxiety relief during endovascular interventions (EVI). "
01/01/2005 - "The review article examines empirical work addressing the efficacy of hypnosis for procedural pain in pediatric oncology."
06/01/2004 - "The efficacy of hypnosis in the reduction of procedural pain and distress in pediatric oncology: a systematic review."
10/01/2023 - "Virtual reality hypnosis for needle-related procedural pain and fear management in children: a non-inferiority randomized trial."

02/25/2022 - "All quantitative and qualitative variables were considered: the patients admitted, the type of PICC inserted, overall procedural time, the mentor's help, the insert failures, the number of punctures required, the procedural pain utilizing Visual Analog Scale (VAS), any procedural complications, chest X-rays needed, the follow up to the eighth day (D8). "
12/01/2012 - "The most frequently reported procedural pain or stressful episodes were peripheral catheterization, clinical examination and vascular puncture. "
05/01/2009 - "One hour after epidural puncture, reported procedural pain was recorded (VAS). "
01/01/2021 - "Studies continue to show that, compared with nerve stimulation, ultrasound guidance alone leads to: significantly improved block success; decreased need for rescue analgesia; decreased procedural pain; and lower rates of vascular puncture. "
01/01/2021 - "The change in pain at each puncture and factors correlated with post-procedural pain were calculated using multiple regression analysis, and factors predicting an answer of "yes" to the question using binary logistic analysis were evaluated. "

09/01/2008 - "To compare the faces pain scale and color analogue scale among children aged 6-12 years undergoing selected procedures (venipuncture, intravenous cannulation, intramuscular injection, lumbar puncture, bone marrow aspiration) and to compare the procedural pain in a child as perceived by the child, parents and health care professionals using the above mentioned scales. "
07/16/2016 - "Sucrose is effective for reducing procedural pain from single events such as heel lance, venipuncture and intramuscular injection in both preterm and term infants. "
12/01/2018 - "SS is a safe and effective approach to neonatal pain due to heel-prick, more effective than oral sucrose or glucose in both term and preterm babies; it seems also effective in other types of acute procedural pain like eye examination or intramuscular injections, but more studies are needed to confirm these preliminary data. "