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Cytochrome P450 Family 11

A cytochrome P450 enzyme family whose members localize to the INNER MITOCHONDRIAL MEMBRANE where they function in the biosynthesis of STEROIDS.

Also Known As:

CYP11 Enzymes; CYP11 Family

Networked: 13 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kim, Tae Hoon: 2 articles (07/2015 - 10/2014)
2.	Lee, Sang Hag: 2 articles (07/2015 - 10/2014)
3.	Park, Se Jin: 2 articles (07/2015 - 10/2014)
4.	Gaur, G K: 1 article (02/2022)
5.	Karikalan, M: 1 article (02/2022)
6.	Krishnaswamy, N: 1 article (02/2022)
7.	Kumar, H: 1 article (02/2022)
8.	Mishra, Girish K: 1 article (02/2022)
9.	Patra, M K: 1 article (02/2022)
10.	Rajin, T R: 1 article (02/2022)

Related Diseases

1.	Adenoma (Adenomas) 10/12/2023 - "Human chorionic gonadotropin (hCG) stimulation tests had weakly positive results, and immunohistochemical staining of adrenal adenoma tissue also revealed positivity for luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and cytochrome P450 family 11 subfamily B member 1 (CYP11B1). "
2.	Neoplasms (Cancer) 07/01/2016 - "Association between the CYP11 family and six cancer types." 07/01/2016 - "As the CYP11 family is important for steroid biosynthesis, and previous studies have demonstrated that steroid hormones are associated with certain cancers, these results indicate a common role of the CYP11 family in various cancer types." 01/01/2022 - "The clinical diagnosis was subclinical Cushing's syndrome in 2 cases, and primary aldosteronism in 1. Despite suspected CA excess in clinical symptoms and imaging findings, the pathological findings of all these tumors were revealed to be cytochrome P450 family 11 subfamily B member 1 (CYP11B1) positive adrenocortical adenomas. "
3.	Pediatric Obesity 01/01/2017 - "Backgrounds/Objectives:This panel study was to predict the incidences of pediatric obesity by the interaction of sodium (Na) intake and nine single-nucleotide polymorphisms (SNPs) of salt-sensitive genes (SSGs), ACE(angiotensin-converting enzyme), ADD1 G460W,AGT M235T,CYP11β2 (cytochrome P450 family 11-subfamily β-2, -aldosterone synthase),GNB3 C285T,GRK4(A142V)(G-protein-coupled receptor kinases type 4),GRK4 (A486V),NEDD4L (neural precursor cell expressed developmentally downregulated 4 like; rs2288774) and SLC12A3 (solute carrier family 12 (Na/Cl transporters)-member 3), selected from genome-wide association study. "
4.	Nasal Polyps (Nasal Polyp) 07/01/2015 - "The present study analyzed the expression of 11β-HSD1, 11β-HSD2, and steroidogenic enzymes (cytochrome P450, family 11, subfamily B, polypeptide 1 [CYP11B1]; cytochrome P450, family 11, subfamily A, polypeptide 1 [CYP11A1]) in nasal polyp tissues, and endogenous cortisol levels in nasal polyp-derived epithelial cells. "
5.	Rhinosinusitis 10/01/2014 - "This study is to investigate the effect of chronic rhinosinusitis (CRS) on expression of 11β-HSD1, 11β-HSD2, steroidogenic enzymes (cytochrome P450, family 11, subfamily B, polypeptide 1 [CYP11B1] and cytochrome P450, family 11, subfamily A, polypeptide 1 [CYP11A1]), and endogenous cortisol levels in human sinus mucosa. "

Related Drugs and Biologics

1.	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)
2.	LH Receptors (LH Receptor)
3.	Luteinizing Hormone (Lutropin)
4.	Chorionic Gonadotropin (Human Chorionic Gonadotropin)
5.	Cholesterol Side-Chain Cleavage Enzyme (CYP11A1)
6.	Enzymes
7.	Peptides (Polypeptides)
8.	Hydrocortisone (Cortisol)
9.	Cytochrome P-450 CYP11B2 (CYP11B2)
10.	Sodium