Psychological Trauma

An emotionally painful, shocking, stressful, and sometimes life-threatening experience. It can result from witnessing distressing events such as natural disasters, physical or sexual abuse, and terrorism or other acts of violence. (https://www.nimh.nih.gov/health/)

Also Known As:

Networked: 254 relevant articles (14 outcomes, 23 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
2.	Wounds and Injuries (Trauma)
3.	Breast Neoplasms (Breast Cancer)
4.	Vesicovaginal Fistula
5.	Postoperative Pain

Experts

1.	Theiss-Abendroth, Peter: 4 articles (05/2007 - 11/2006)
2.	Case, Adam J: 2 articles (05/2022 - 01/2019)
3.	Elkhatib, Safwan K: 2 articles (05/2022 - 01/2019)
4.	Moshfegh, Cassandra M: 2 articles (05/2022 - 01/2019)
5.	Youssef, Nagy A: 2 articles (01/2022 - 05/2018)
6.	Hjort Svendsen, Ann Louise: 2 articles (10/2021 - 07/2021)
7.	Sternhagen Nielsen, Anni Brit: 2 articles (10/2021 - 07/2021)
8.	Bremner, J Douglas: 2 articles (11/2020 - 01/2020)
9.	Gurel, Nil Z: 2 articles (11/2020 - 01/2020)
10.	Huang, Minxuan: 2 articles (11/2020 - 01/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Psychological Trauma:

1.	IsotopesIBA 04/01/2001 - "The low yield of positive results and lack of evidence of impact on management indicate that DMSA scanning, with all the implications of isotope exposure, intravenous injection, staff time, psychological trauma, and expense, could be omitted in children over 1 year with first simple UTI not sufficiently ill to be admitted to hospital. "
2.	Succimer (Dimercaptosuccinic Acid)FDA Link 04/01/2001 - "The low yield of positive results and lack of evidence of impact on management indicate that DMSA scanning, with all the implications of isotope exposure, intravenous injection, staff time, psychological trauma, and expense, could be omitted in children over 1 year with first simple UTI not sufficiently ill to be admitted to hospital. "
3.	Hydrocortisone (Cortisol)FDA LinkGeneric 01/01/2020 - "Thus the predictive value of pre- and post-traumatic hair cortisol concentrations (HCCs) for psychological trauma sequelae was investigated in response to motor vehicle crash (MVC). " 01/01/1997 - "This article explores the consequences of an additional dysfunction: a dissociation of the hemispheres that appears to be responsible for the alexithymic avoidance and failure of the cortisol response that so often follow severe psychological trauma. " 10/01/1993 - "This article explores the consequences of an additional dysfunction: a dissociation of the hemispheres that appears to be responsible for the alexithymic avoidance and failure of the cortisol response that so often follow severe psychological trauma. " 05/01/2010 - "Several studies have indicated that psychogenic nonepileptic seizures (PNES) are associated with psychological trauma, but only a few studies have examined the associations with neurobiologic stress systems, such as the hypothalamus-pituitary-adrenal (HPA) axis and its end-product cortisol. " 01/01/2020 - "Overall, this study shows substantial reductions in intrusive memories and preserved voluntary narrative-declarative memory following either propranolol or hydrocortisone in an experimental model of psychological trauma. "
4.	Propranolol (Inderal)FDA LinkGeneric 01/01/2012 - "Forty-one emergency department patients who had experienced a qualifying acute psychological trauma were randomized to receive up to 240 mg/day of propranolol or placebo for 19 days. " 01/01/2020 - "Overall, this study shows substantial reductions in intrusive memories and preserved voluntary narrative-declarative memory following either propranolol or hydrocortisone in an experimental model of psychological trauma. "
5.	Immunotoxins (Immunotoxin)IBA 05/01/2010 - "Risk factors include age, sex, ethnicity, exogenous boosting of immunity from varicella contacts, underlying cell-mediated immune disorders, mechanical trauma, psychological stress, and immunotoxin exposure. " 01/01/2004 - "Risk factors identified in analytical studies that could explain this variation included age, sex, ethnicity, genetic susceptibility, exogenous boosting of immunity from varicella contacts, underlying cell-mediated immune disorders, mechanical trauma, psychological stress, and immunotoxin exposure. "
6.	salicylhydroxamic acid (SHAM)IBA 01/01/2020 - "Using a double-blind approach, we investigated the effects of active or sham tcVNS on peripheral cardiovascular and autonomic responses to stress using wearable sensing devices in 24 healthy human participants with a history of exposure to psychological trauma. " 11/01/2020 - "A total of 30 subjects with a history of exposure to psychological trauma experience were recruited (12 with PTSD diagnosis) for a three-day randomized double-blinded study of tcVNS or sham stimulation. "
7.	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA 01/01/2020 - "MDMA-assisted psychotherapy may help people who have experienced psychological trauma and who have not been able to resolve their problems through existing treatments, however more research is needed. " 01/01/2020 - "Small-scale studies have shown reduced psychological trauma, however there has been widespread misunderstanding of the aims and implications of this work, most commonly the notion that MDMA is a 'treatment for PTSD', which to date has not been researched. "
8.	Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)IBA 01/01/2006 - "The pathophysiological changes were inhibited by injecting pups sc with a corticotropin-releasing hormone (CRH) receptor antagonist daily during MS. Our studies indicate that early psychological trauma predisposes neonatal rats to develop persistent mucosal barrier dysfunction, including impaired host defense to luminal bacteria, by a mechanism involving peripheral CRH receptors."
9.	VaccinesIBA 01/01/2022 - "This study examined the profiles and correlates of psychological trauma, compliance with preventative measures, vaccine acceptance and participation in voluntary testing during the novel coronavirus disease 2019 (COVID-19) pandemic among the adult population in Hong Kong (n = 3,011). "
10.	Thyroid HormonesIBA 01/01/2022 - "In the present study we measured the concentrations of cortisol, thyroid hormones, testosterone, and GABA (gamma aminobutyric acid) in am blood plasma samples of combatants with an at least 10 year history of military psychological trauma (N = 74) divided in groups that either suffer from post-traumatic stress disorder (PTSD) (N = 37) or are resistant (N = 37) as well as in a control group without traumatic experience in the anamnesis, (N = 34). "

Therapies and Procedures

1.	Mastectomy (Mammectomy) 01/01/1988 - "It has been demonstrated that the psychological trauma has been dramatically reduced and that many patients will accept mastectomy almost with a sense of relief, when immediate reconstruction can be offered." 04/01/2010 - "Nipple areola (NA) sparing mastectomy has an acceptable complication rate, is oncologically safe and facilitates an improved cosmetic result, aiding greatly in reducing psychological trauma associated with breast loss. " 08/01/2023 - "Immediate reconstruction preserves the skin of the breast and its natural form and prevents the psychological trauma associated with mastectomy. " 01/01/2017 - "Mastectomy is an essential intervention to save lives, but it can destroy one's body image, causing both physical and psychological trauma. " 08/31/2015 - "Immediate reconstruction preserves the skin of the breast and its natural form and prevents the psychological trauma associated with mastectomy. "
2.	Therapeutics 11/01/2023 - "A dearth of research has explored effectiveness of therapies for treating psychological trauma post perinatal bereavement and post-childbirth, with need to develop and test a research informed flexible counselling package." 11/01/2023 - "A scoping review mapped coverage, range, and type of research that has reported on prior therapies used to treat psychological trauma post perinatal bereavement. " 11/01/2023 - "To scope for research that has implemented therapies to treat psychological trauma post perinatal bereavement, for potential inclusion in a flexible treatment package. " 11/01/2023 - "Before setting-up a treatment service for postnatal women who are experiencing psychological trauma, it is important to identify what therapies have been used in-the-past to address this problem. " 11/01/2023 - "A scoping review of therapies used to treat psychological trauma post perinatal bereavement."
3.	Art Therapy 01/01/2021 - "This study also provides support to the idea that art therapy and technique of behavior therapy can be helpful in treatment of post trauma psychological issues in children." 12/01/2013 - "We evaluated Accelerated Resolution Therapy (ART) for the treatment of combat-related psychological trauma. " 09/01/2015 - "We compared treatment of symptoms of psychological trauma between civilian and military adults by use of Accelerated Resolution Therapy (ART), an emerging, brief exposure-based therapy. "
4.	Complementary Therapies (Alternative Medicine) 06/01/2009 - "Studies on the efficacy of different treatment modalities for psychological trauma, including mind-body complementary therapies, are needed."
5.	Anesthesia 01/01/2018 - "Medically refractory OT can respond favorably to asleep bilateral DBS surgery similar to awake surgery, and may have the advantages of less psychological trauma to the patient, shorter procedure times, and less exposure to anesthesia." 01/01/2022 - "Conversely, too light anesthesia combined with muscle relaxants can result in intraoperative patient awareness and lead to serious psychological trauma. " 07/01/2005 - "Infantile psychological trauma may be caused by surgeries and anesthesia. " 07/01/1989 - "Advantages of parental presence in the OR during anesthesia induction are decreased psychological trauma (child), smoother induction (child), and decreased parental anxiety. " 07/01/1957 - "Psychological trauma to the patient during hospitalization is to be avoided, sedation properly gauged for each patient, and complete block anesthesia used to preserve the cough reflex. "