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chikusetsusaponin V

isolated from Rhizoma Panacis Japonici; structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - chikusetsusaponin V: 3

Experts

1.	Li, Bin: 2 articles (03/2021 - 01/2018)
2.	Wang, Wei: 2 articles (03/2021 - 01/2018)
3.	Guo, Shiyin: 1 article (03/2021)
4.	Hu, Yi: 1 article (03/2021)
5.	Jian, Yuqing: 1 article (03/2021)
6.	Lei, Xinnuo: 1 article (03/2021)
7.	Liu, Leping: 1 article (03/2021)
8.	Peng, Caiyun: 1 article (03/2021)
9.	Qin, Yan: 1 article (03/2021)
10.	Qiu, Yixing: 1 article (03/2021)

Related Diseases

1.	Acute Lung Injury 05/01/2019 - "Chikusetsusaponin V attenuates lipopolysaccharide-induced acute lung injury in mice by modulation of the NF-κB and LXRα."
2.	Obesity 03/01/2021 - "To explore the in vivo anti-obesity effect of chikusetsusaponin V and explore the underlying mechanism by transcriptomic and metabonomic methods. " 03/01/2021 - "Transcriptomic and metabonomic profiling reveal the anti-obesity effects of Chikusetsusaponin V, a compound extracted from Panax japonicus." 03/01/2021 - "The integrative analysis highlighted that chikusetsusaponin V significantly influenced the activated protein kinase signaling pathway at both transcriptomic and metabolomic levels, thereby exerting anti-obesity effects." 03/01/2021 - "Chikusetsusaponin V could significantly alleviate the high-fat-diet induced increase in the weight of the whole body and obesity-related organs or tissues, and ameliorate the lipid content in the blood, the lipid accumulation in the livers, as well as the hypertrophy of the fat tissues. "
3.	Neoplasms (Cancer) 01/01/2018 - "The results indicated that RNase A level in tumor cells was upregulated by G-10 and Chikusetsusaponin V in a concentration-dependent manner, while the average level of RNase A in the HBV infection group was significantly inhibited compared with that in the control group. "
4.	Infections 01/01/2018 - "The results indicated that RNase A level in tumor cells was upregulated by G-10 and Chikusetsusaponin V in a concentration-dependent manner, while the average level of RNase A in the HBV infection group was significantly inhibited compared with that in the control group. "
5.	Hypertrophy 03/01/2021 - "Chikusetsusaponin V could significantly alleviate the high-fat-diet induced increase in the weight of the whole body and obesity-related organs or tissues, and ameliorate the lipid content in the blood, the lipid accumulation in the livers, as well as the hypertrophy of the fat tissues. "

Related Drugs and Biologics

1.	Pancreatic Ribonuclease (Ribonuclease A)
2.	Protein Kinases (Protein Kinase)
3.	Lipopolysaccharides
4.	Lipids