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NVP-QAV680

structure in first source

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indolizines: 3
      - NVP-QAV680: 1

Experts

1.	Barker, Lucy: 1 article (05/2017)
2.	Brown, Lyndon: 1 article (05/2017)
3.	Brown, Zarin: 1 article (05/2017)
4.	Budd, David: 1 article (05/2017)
5.	Charlton, Steven J: 1 article (05/2017)
6.	Chatterjee, Devnandan: 1 article (05/2017)
7.	Cox, Brian: 1 article (05/2017)
8.	Dubois, Gerald: 1 article (05/2017)
9.	Duggan, Nicholas: 1 article (05/2017)
10.	Hall, Edward: 1 article (05/2017)

Related Diseases

1.

Asthma (Bronchial Asthma)

05/11/2017 - "Further optimization of an initial DP2 receptor antagonist clinical candidate NVP-QAV680 led to the discovery of a follow-up molecule 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid (compound 11, NVP-QAW039, fevipiprant), which exhibits improved potency on human eosinophils and Th2 cells, together with a longer receptor residence time, and is currently in clinical trials for severe asthma."

Related Drugs and Biologics

1.	Acetic Acid (Vinegar)
2.	fevipiprant