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KSI-3716

structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - KSI-3716: 2
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        4-Quinolones: 66
        KSI-3716: 2

Experts

1.	Ahn, Kyung-Ohk: 2 articles (02/2014 - 01/2014)
2.	Jeong, Kyung-Chae: 2 articles (02/2014 - 01/2014)
3.	Lee, Sang-Jin: 2 articles (02/2014 - 01/2014)
4.	Park, Weon Seo: 2 articles (02/2014 - 01/2014)
5.	Seo, Ho Kyung: 2 articles (02/2014 - 01/2014)
6.	Ji, Min-Ju: 1 article (02/2014)
7.	Kim, In-Hoo: 1 article (02/2014)
8.	Kim, Kyung-Tae: 1 article (02/2014)
9.	Seo, Hye-Hyun: 1 article (02/2014)
10.	Shin, Seung-Pil: 1 article (02/2014)

Related Diseases

1.	Neoplasms (Cancer) 02/01/2014 - "Intravesical instillation of KSI-3716 at a dose of 5 mg/kg significantly suppressed tumor growth with minimal systemic toxicity. " 02/01/2014 - "We explored whether intravesical instillation of the c-MYC inhibitor KSI-3716 could suppress tumor growth in murine orthotopic bladder xenografts. " 01/30/2014 - "In a previous study, we reported that intravesical administration of the c-Myc inhibitor KSI-3716 suppresses tumor growth in an orthotopic bladder cancer model. "
2.	Urinary Bladder Neoplasms (Bladder Cancer) 02/01/2014 - "KSI-3716 exerted cytotoxic effects on bladder cancer cells by inducing cell cycle arrest and apoptosis. " 02/01/2014 - "The c-MYC inhibitor KSI-3716 could be developed as an effective intravesical chemotherapy agent for bladder cancer." 02/01/2014 - "Intravesical instillation of c-MYC inhibitor KSI-3716 suppresses orthotopic bladder tumor growth." 01/30/2014 - "These results suggest that sequential treatment with gemcitabine and KSI-3716 may be beneficial to bladder cancer patients. " 01/30/2014 - "Here, we explored whether KSI-3716 inhibits gemcitabine-resistant bladder cancer cell proliferation. "

Related Drugs and Biologics

1.	Gemcitabine

Related Therapies and Procedures

1.	Intravesical Administration
2.	Drug Therapy (Chemotherapy)