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JMV4463

structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Pepstatins
      - JMV4463: 2

Experts

1.	Amblard, Muriel: 2 articles (02/2016 - 10/2013)
2.	Garcia, Marcel: 2 articles (02/2016 - 10/2013)
3.	Hernandez, Jean-François: 2 articles (02/2016 - 10/2013)
4.	Martin, Vincent: 2 articles (02/2016 - 10/2013)
5.	Martinez, Jean: 2 articles (02/2016 - 10/2013)
6.	Maynadier, Marie: 2 articles (02/2016 - 10/2013)
7.	Vezenkov, Lubomir L: 2 articles (02/2016 - 10/2013)
8.	Bellet, Virginie: 1 article (02/2016)
9.	Bettache, Nadir: 1 article (02/2016)
10.	Lisowski, Vincent: 1 article (02/2016)

Related Diseases

1.	Neoplasms (Cancer) 10/28/2013 - "When tested in mice xenografted with breast cancer cells, JMV4463 delayed tumor emergence and growth. " 10/28/2013 - "We showed that this pepstatin conjugate (JMV4463) exhibited high anti-proliferative effect on tumor cell cultures via intracellular CathD inhibition and altered cell cycle associated with apoptotic events in vitro. " 02/04/2016 - "In this context, the pepstatin bioconjugate JMV4463 [Ac-arg-O2 Oc-(Val)3-Sta-Ala-Sta-(AMPA)4-NH2; O2 Oc=8-amino-3,6-dioxaoctanoyl, Sta=statine, AMPA=ortho-aminomethylphenylacetyl], containing a new kind of cell-penetrating vector, was previously shown to exhibit potent antiproliferative effects in vitro and to delay the onset of tumors in vivo. "
2.	Breast Neoplasms (Breast Cancer) 10/28/2013 - "When tested in mice xenografted with breast cancer cells, JMV4463 delayed tumor emergence and growth. "

Related Drugs and Biologics

1.	pepstatin (pepstatin A)
2.	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)
3.	statine