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4-dodecylaminophenol

structure in first source

Also Known As:

p-dodecylaminophenol

Networked: 7 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - Aminophenols: 16
      - 4-dodecylaminophenol: 7
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Aminophenols: 16
        4-dodecylaminophenol: 7

Experts

1.	Takahashi, Noriko: 6 articles (10/2017 - 01/2007)
2.	Imai, Masahiko: 4 articles (10/2017 - 11/2010)
3.	Ohba, Toshihiro: 3 articles (11/2010 - 01/2007)
4.	Higashiyama, Kimio: 2 articles (02/2008 - 01/2007)
5.	Hasegawa, Shinya: 1 article (10/2017)
6.	Koyama, Shunpei: 1 article (10/2017)
7.	Yamasaki, Masahiro: 1 article (10/2017)
8.	Takeda, Kotaro: 1 article (10/2013)
9.	Egawa, Rumi: 1 article (11/2010)
10.	Imaizumi, Masue: 1 article (11/2010)

Related Diseases

1.	Neoplasms (Cancer) 11/28/2010 - "As part of these studies we have examined anti-cancer effects on the neuroblastoma NB-39-nu cells of p-dodecylaminophenol (p-DDAP), a novel derivative of N-(4-hydroxyphenyl) retinamide (4-HPR). " 01/01/2023 - "Assuming that the cyclohexene ring of 4-HPR is the cause of the side effects, methylaminophenol was discovered through structure-activity relationship research, and p-dodecylaminophenol (p-DDAP, 3), which has no side effects or toxicity and is effective against a wide range of cancers, was developed. " 01/15/2007 - "In this study, we investigated anticancer activities against various cancer cell lines by the new aminophenols, p-dodecylaminophenol (1), p-decylaminophenol (2), N-(4-hydroxyphenyl)dodecananamide (3), and N-(4-hydroxyphenyl)decananamide (4), which exhibits a side chain as long as 5. Cell growth of breast cancer (MCF-7, MCF-7/Adr(R)), prostate cancer (DU-145), and leukemia (HL60) cells was suppressed by 1 and 2 in a fashion dependent on the length of the alkyl chain attached to the aminophenol. "
2.	Neuroblastoma 10/15/2017 - "Anticancer efficacy of p-dodecylaminophenol against high-risk and refractory neuroblastoma cells in vitro and in vivo." 11/28/2010 - "As part of these studies we have examined anti-cancer effects on the neuroblastoma NB-39-nu cells of p-dodecylaminophenol (p-DDAP), a novel derivative of N-(4-hydroxyphenyl) retinamide (4-HPR). "
3.	Prostatic Neoplasms (Prostate Cancer) 02/01/2008 - "p-Dodecylaminophenol derived from the synthetic retinoid, fenretinide: antitumor efficacy in vitro and in vivo against human prostate cancer and mechanism of action." 01/15/2007 - "In this study, we investigated anticancer activities against various cancer cell lines by the new aminophenols, p-dodecylaminophenol (1), p-decylaminophenol (2), N-(4-hydroxyphenyl)dodecananamide (3), and N-(4-hydroxyphenyl)decananamide (4), which exhibits a side chain as long as 5. Cell growth of breast cancer (MCF-7, MCF-7/Adr(R)), prostate cancer (DU-145), and leukemia (HL60) cells was suppressed by 1 and 2 in a fashion dependent on the length of the alkyl chain attached to the aminophenol. "
4.	Leukemia 01/15/2007 - "In this study, we investigated anticancer activities against various cancer cell lines by the new aminophenols, p-dodecylaminophenol (1), p-decylaminophenol (2), N-(4-hydroxyphenyl)dodecananamide (3), and N-(4-hydroxyphenyl)decananamide (4), which exhibits a side chain as long as 5. Cell growth of breast cancer (MCF-7, MCF-7/Adr(R)), prostate cancer (DU-145), and leukemia (HL60) cells was suppressed by 1 and 2 in a fashion dependent on the length of the alkyl chain attached to the aminophenol. "
5.	Breast Neoplasms (Breast Cancer) 01/15/2007 - "In this study, we investigated anticancer activities against various cancer cell lines by the new aminophenols, p-dodecylaminophenol (1), p-decylaminophenol (2), N-(4-hydroxyphenyl)dodecananamide (3), and N-(4-hydroxyphenyl)decananamide (4), which exhibits a side chain as long as 5. Cell growth of breast cancer (MCF-7, MCF-7/Adr(R)), prostate cancer (DU-145), and leukemia (HL60) cells was suppressed by 1 and 2 in a fashion dependent on the length of the alkyl chain attached to the aminophenol. "

Related Drugs and Biologics

1.	Fenretinide
2.	cyclohexene
3.	Aminophenols
4.	retinamide
5.	p-decylaminophenol
6.	Retinoids
7.	Amides