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1- (4- (2- ((6- (4- (2- (dimethylamino)ethoxy)phenyl)furo(2,3- d)pyrimidin- 4- yl)amino)ethyl)phenyl)- 3- phenylurea

an aurora kinase inhibitor; structure in first source

Also Known As:

IBPR001

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - 1-(4-(2-((6-(4-(2-(dimethylamino)ethoxy)phenyl)furo(2,3-d)pyrimidin-4-yl)amino)ethyl)phenyl)-3-phenylurea: 1
Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Phenylurea Compounds: 1
      - 1-(4-(2-((6-(4-(2-(dimethylamino)ethoxy)phenyl)furo(2,3-d)pyrimidin-4-yl)amino)ethyl)phenyl)-3-phenylurea: 1
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenylurea Compounds: 1
        1-(4-(2-((6-(4-(2-(dimethylamino)ethoxy)phenyl)furo(2,3-d)pyrimidin-4-yl)amino)ethyl)phenyl)-3-phenylurea: 1

Experts

1.	Chang, Chun-Wei: 1 article (07/2013)
2.	Chang, Kai-Yen: 1 article (07/2013)
3.	Chao, Yu-Sheng: 1 article (07/2013)
4.	Chen, Chiung-Tong: 1 article (07/2013)
5.	Chen, Chun-Hwa: 1 article (07/2013)
6.	Chi, Ya-Hui: 1 article (07/2013)
7.	Chu, Chang-Ying: 1 article (07/2013)
8.	Coumar, Mohane Selvaraj: 1 article (07/2013)
9.	Fung, Ka-Shu: 1 article (07/2013)
10.	Hsieh, Hsing-Pang: 1 article (07/2013)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 07/11/2013 - "Rational optimization has led to the identification of Aurora kinase inhibitor 27 (IBPR001; LE = 0.26; LipE = 4.78), with improved in vitro potency and physicochemical properties, resulting in an in vivo active (HCT-116 colon cancer xenograft mouse model) anticancer agent."

Related Drugs and Biologics

1.	Aurora Kinases
2.	Antineoplastic Agents (Antineoplastics)