acyldepsipeptides

Also Known As:

ADEP4 acyldepsipeptide; ADEPs acyldepsipeptides; acyldepsipeptide; acyldepsipeptide 4; acyldepsipeptide-4; cyclic acyldepsipeptide; cyclic acyldepsipeptides; enopeptin A; enopeptin B

Networked: 8 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - acyldepsipeptides: 8
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - acyldepsipeptides: 8

Experts

1.	Brötz-Oesterhelt, Heike: 2 articles (11/2019 - 10/2005)
2.	Gao, Yang: 2 articles (03/2014 - 08/2013)
3.	Guo, Peng: 2 articles (03/2014 - 08/2013)
4.	He, Dalin: 2 articles (03/2014 - 08/2013)
5.	Shi, Qi: 2 articles (03/2014 - 08/2013)
6.	Xu, Shan: 2 articles (03/2014 - 08/2013)
7.	Zhang, Hailong: 2 articles (03/2014 - 08/2013)
8.	Mayer, Christian: 1 article (11/2019)
9.	Sass, Peter: 1 article (11/2019)
10.	Gil, Fernando: 1 article (01/2016)

Related Diseases

1.	Bacterial Infections (Bacterial Infection) 10/15/2010 - "Although the natural products have poor pharmacological properties, a synthetic derivative called acyldepsipeptide 4 (ADEP 4) showed remarkable antibacterial activity both in vitro and in mouse models of bacterial infections. " 11/01/2019 - "Antibiotic acyldepsipeptides (ADEPs) exert potent antibacterial activity in rodent models of bacterial infection and exceptional efficacy against persister cells of methicillin-resistant Staphylococcus aureus (MRSA). " 12/20/2022 - "The acyldepsipeptide antibiotic ADEP targets ClpP and has shown promise for treating multiresistant and persistent bacterial infections. " 10/01/2005 - "Here we show that a new class of antibiotics-acyldepsipeptides-has antibacterial activity against Gram-positive bacteria in vitro and in several rodent models of bacterial infection. "
2.	Kidney Neoplasms (Kidney Cancer) 03/01/2014 - "[Acyldepsipeptide 1 induces apoptosis in renal cancer cells by down-regulation of Gli and Bcl-2 via SHH pathway]." 08/30/2013 - "Acyldepsipeptides inhibit the growth of renal cancer cells through G1 phase cell cycle arrest." 03/01/2014 - "To investigate the effects of acyldepsipeptide 1 (ADEP1) on renal cancer cell apoptosis and on the expressions of SHH signaling pathway related protein Gli-1 and Bcl-2. "
3.	Infections 01/01/2016 - "difficile infections of acyldepsipeptides family of antibiotics, its mechanism of action and current developmental stages." 09/15/2022 - "Acyldepsipeptides (ADEPs) are a new class of emerging antimicrobial peptides (AMPs), which are currently explored for treatment of pathogenic infections, including tuberculosis (TB). "
4.	Tuberculosis (Tuberculoses) 09/15/2022 - "Acyldepsipeptide Analogues: A Future Generation Antibiotics for Tuberculosis Treatment." 09/15/2022 - "Acyldepsipeptides (ADEPs) are a new class of emerging antimicrobial peptides (AMPs), which are currently explored for treatment of pathogenic infections, including tuberculosis (TB). "
5.	Reinfection 01/01/2016 - "Acyldepsipeptide antibiotics as a potential therapeutic agent against Clostridium difficile recurrent infections."

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Proteins (Proteins, Gene)
3.	Antimicrobial Peptides