dehydropachymic acid

isolated from Poria cocos

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Anđelković, Boban: 1 article (01/2021)
2.	Milosavljević, Slobodan: 1 article (01/2021)
3.	Novaković, Miroslav: 1 article (01/2021)
4.	Sofrenić, Ivana: 1 article (01/2021)
5.	Stanojković, Tatjana: 1 article (01/2021)
6.	Tešević, Vele: 1 article (01/2021)
7.	Todorović, Nina: 1 article (01/2021)
8.	Vujisić, Ljubodrag: 1 article (01/2021)
9.	Backlund, Anders: 1 article (11/2016)
10.	Chang, Fang-Rong: 1 article (11/2016)

1.	Pancreatic Neoplasms (Pancreatic Cancer) 06/01/2013 - "Here, we show that a characterized mixture of triterpenes extracted from P. cocos (PTE) and three purified triterpenes: pachymic acid (PA), dehydropachymic acid (DPA) and polyporenic acid C (PPAC) suppress the proliferation of the human pancreatic cancer cell lines Panc-1, MiaPaca-2, AsPc-1 and BxPc-3. "
2.	Neoplasms (Cancer) 11/23/2016 - "Dehydropachymic acid (9), dehydroeburicoic acid (12), pachymic acid (14), and lanosta-7,9(11),24-trien-21-oic acid (20) exhibited an antiproliferative effect on the CCRF-CEM cancer cell line with IC50 values of 2.7, 6.3, 4.9, and 13.1 μM, respectively. "
3.	Leukemia 01/01/2021 - "Among the known compounds, notable cytotoxicities against HL60 leukemia cells and selectivity with respect to MRC-5 healthy cells were noticed for dehydropachymic acid (IC50 = 10.9 μM, SI 8.6), pachymic acid (IC50 = 11.0 μM, SI 9.8), 3-epi-dehydrotumulosic acid (IC50 = 19.9 μM, SI 5.8) and 12α-hydroxy-3α-(3'-hydroxy-4'-methoxycarbonyl-3'-methylbutyryloxy)-24-methyllanosta-8,24 (31)-dien-26-oic acid (IC50 = 19.2 μM, SI 2.2)."