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XLR-11

synthetic cannabinoid; structure in first source

Also Known As:

(1-(5-fluoropentyl)indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone; XLR11

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Cannabinoids: 5901
      - XLR-11: 7

Experts

1.	Al-Eitan, Laith: 1 article (12/2020)
2.	Alahmad, Saif: 1 article (12/2020)
3.	Alhusban, Ahmed: 1 article (12/2020)
4.	Bauman, Michael H: 1 article (01/2020)
5.	Bi, Guo-Hua: 1 article (01/2020)
6.	Galaj, Ewa: 1 article (01/2020)
7.	Gardner, Eliot L: 1 article (01/2020)
8.	He, Yi: 1 article (01/2020)
9.	Wang, Xiao-Fei: 1 article (01/2020)
10.	Xi, Zheng-Xiong: 1 article (01/2020)

Related Diseases

1.	Brain Injuries (Brain Injury) 12/01/2020 - "The current study shows that XLR-11 increases the viability of human brain microvascular endothelial cells and enhances angiogenesis in the brain in vitro, suggesting that XLR-11 could potentially be used as a therapeutic angiogenic drug in human brain injury treatment."
2.	Catalepsy 01/01/2020 - "Unexpectedly, genetic deletion of CB2 receptor abolished analgesia and catalepsy produced by Δ9 -THC or WIN55212-2, but not by XLR11. " 12/01/2013 - "Similar to other psychoactive cannabinoid agonists, XLR-11 and UR-144 showed low nanomolar (<30) affinity for CB1 and CB2 receptors, activated these receptors as full agonists, and produced dose-dependent effects that were blocked by rimonabant in mice, including antinociception, hypothermia, catalepsy and suppression of locomotor activity. "
3.	Acute Kidney Injury (Acute Renal Failure) 11/01/2014 - "XLR-11 has previously been associated with acute kidney injury in humans. "
4.	Stroke (Strokes) 11/01/2014 - "The close temporal association between XLR-11 inhalation and his stroke is concerning. "
5.	Necrosis 11/06/2022 - "Histopathological analysis of the liver of XLR-11 treated mice confirmed pronounced hepatic necrosis associated with inflammatory cell infiltration. "

Related Drugs and Biologics

1.	Cannabinoid Receptor Agonists
2.	CB2 Cannabinoid Receptor
3.	Dronabinol (THC)
4.	Rimonabant
5.	(1- pentyl- 1H- indol- 3- yl)(2,2,3,3- tetramethylcyclopropyl)methanone
6.	(3R)- ((2,3- dihydro- 5- methyl- 3- ((4- morpholinyl)methyl)pyrrolo- (1,2,3- de)- 1,4- benzoxazin- 6- yl)(1- naphthalenyl))methanone (WIN 55,212)

Related Therapies and Procedures

1.	Analgesia