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2- pyridine- 3- yl- methylene- indan- 1,3- dione

inhibits polycomb-repressive complex 1

Also Known As:

PRT4165

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Indenes: 4
        Indans: 7
        2-pyridine-3-yl-methylene-indan-1,3-dione: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Indenes: 4
    - Indans: 7
      - 2-pyridine-3-yl-methylene-indan-1,3-dione: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - 2-pyridine-3-yl-methylene-indan-1,3-dione: 1

Experts

1.	Itoh, Mai: 1 article (11/2017)
2.	Ohtaka, Mika: 1 article (11/2017)
3.	Tohda, Shuji: 1 article (11/2017)

Related Diseases

1.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/01/2017 - "Four acute myeloid leukemia and two T-lymphoblastic leukemia cell lines were treated with BMI1 inhibitors artemisinin, PRT4165, and PTC-209 and analyzed for cell proliferation and gene expression by microarray and immunoblotting. "
2.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/01/2017 - "Four acute myeloid leukemia and two T-lymphoblastic leukemia cell lines were treated with BMI1 inhibitors artemisinin, PRT4165, and PTC-209 and analyzed for cell proliferation and gene expression by microarray and immunoblotting. "

Related Drugs and Biologics

1.	PTC-209
2.	artemisinin (artemisinine)