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RO5166017

structure in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - RO5166017: 4
Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Phenethylamines: 28
      - RO5166017: 4

Experts

1.	Li, Jun-Xu: 2 articles (12/2021 - 10/2017)
2.	Wu, Ruyan: 1 article (12/2021)
3.	Siemian, Justin N: 1 article (10/2017)
4.	Zhang, Yanan: 1 article (10/2017)
5.	Alvarsson, Alexandra: 1 article (10/2015)
6.	Kadkhodaei, Banafsheh: 1 article (10/2015)
7.	Millan, Mark J: 1 article (10/2015)
8.	Perlmann, Thomas: 1 article (10/2015)
9.	Schintu, Nicoletta: 1 article (10/2015)
10.	Stan, Tiberiu L: 1 article (10/2015)

Related Diseases

1.	Dyskinesias (Dyskinesia) 10/14/2015 - "Conversely, RO5166017 counteracted both l-DOPA-induced rotation and dyskinesia as well as AMPA receptor phosphorylation. "
2.	Substance-Related Disorders (Drug Abuse) 12/01/2021 - "Selective and potent engineered TAAR1 ligands, including full (RO5166017 and RO5256390) and partial (RO5203648, RO5263397 and RO5073012) agonists and the antagonist EPPTB (N-(3-ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl) benzamide, RO5212773), serve as invaluable tools for the investigation of TAAR1 functions and display significant potential for the development of TAAR1-based pharmacotherapies for the treatment of substance use disorders. "
3.	Hypothermia 10/01/2017 - "Trace amine-associated receptor 1 agonists RO5263397 and RO5166017 attenuate quinpirole-induced yawning but not hypothermia in rats."
4.	Mental Disorders (Mental Disorder) 05/17/2011 - "These results tie TAAR1 to the control of monoamine-driven behaviors and suggest anxiolytic- and antipsychotic-like properties for agonists such as RO5166017, opening treatment opportunities for psychiatric disorders."

Related Drugs and Biologics

1.	4- (3- fluoro- 2- methylphenyl)- 4,5- dihydrooxazol- 2- ylamine
2.	Quinpirole
3.	AMPA Receptors (AMPA Receptor)
4.	Anti-Anxiety Agents (Anxiolytics)
5.	Antipsychotic Agents (Antipsychotics)
6.	Ligands
7.	Levodopa (L Dopa)
8.	4- (3,4- dichlorophenyl)- 4,5- dihydrooxazol- 2- ylamine
9.	(4- chlorophenyl)- (1H- imidazol- 4- ylmethyl)- isopropyl- amine
10.	Trace amine-associated receptor 1

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)