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(M)-bicelaphanol A

from Celastrus orbiculatus; structure in first source

Also Known As:

(P)-bicelaphanol A

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - (M)-bicelaphanol A: 1

Experts

1.	Fu, Yan: 1 article (09/2013)
2.	Tang, Xi Can: 1 article (09/2013)
3.	Wang, Luo Yi: 1 article (09/2013)
4.	Wang, Xu Jie: 1 article (09/2013)
5.	Wu, Jian: 1 article (09/2013)
6.	Zhang, Hai Yan: 1 article (09/2013)
7.	Zhao, Wei Min: 1 article (09/2013)

Related Diseases

1.	Neuroblastoma 09/15/2013 - "In this study, we investigated the neuroprotective effects of (M)-bicelaphanol A, which has been the first dimeric podocarpane type trinorditerpene isolated from Celastrus orbiculatus, against hydrogen peroxide (H2O2)-induced injury in human SH-SY5Y neuroblastoma cells. "
2.	Mitochondrial Diseases (Mitochondrial Disease) 09/15/2013 - "In conclusion, our results for the first time demonstrate that the protection of (M)-bicelaphanol A on SH-SY5Y cells against H2O2-induced oxidative stress may attribute, at least partially, to its attenuation of mitochondrial dysfunction and activation of Akt signaling pathway. "
3.	Neurodegenerative Diseases (Neurodegenerative Disease) 09/15/2013 - "Above results shed more light on the molecular mechanisms involved in the neuroprotective effects of (M)-bicelaphanol A, which could be a potential drug candidate for the treatment of oxidative stress-associated neurodegenerative diseases. "

Related Drugs and Biologics

1.	Neuroprotective Agents
2.	Hydrogen Peroxide (Hydroperoxide)