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4-(3-fluoro-4- methoxyphenyl)- N- (4- phenoxyphenyl)- 1,3- thiazol- 2- amine

an aminothiazole that inhibits of microsomal prostaglandin E synthase-1

Also Known As:

TH-644

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - 4-(3-fluoro-4- methoxyphenyl)-N-(4-phenoxyphenyl)-1,3-thiazol-2-amine: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - 4-(3-fluoro-4- methoxyphenyl)-N-(4-phenoxyphenyl)-1,3-thiazol-2-amine: 1

Experts

1.	Andersson, Göran: 1 article (01/2019)
2.	Desai, Suchita: 1 article (01/2019)
3.	Gerasimcik, Natalija: 1 article (01/2019)
4.	Grenlöv, Simon: 1 article (01/2019)
5.	Kats, Anna: 1 article (01/2019)
6.	Lagnöhed, Ekaterina: 1 article (01/2019)
7.	Nederberg, Jonas: 1 article (01/2019)
8.	Näreoja, Tuomas: 1 article (01/2019)
9.	Yucel-Lindberg, Tülay: 1 article (01/2019)

Related Diseases

1.	Bone Resorption 01/01/2019 - "The aim of this study was to investigate effects of mPGES-1 inhibitors, aminothiazoles TH-848 and TH-644, on PGE2 production and osteoclastogenesis in co-cultures of periodontal ligament (PDL) and osteoclast progenitor cells RAW 264.7, stimulated by lipopolysaccharide (LPS), and bone resorption in RANKL-mediated peripheral blood mononuclear cells (PBMCs). "

Related Drugs and Biologics

1.	Dinoprostone (PGE2)
2.	Lipopolysaccharides
3.	4-((4-(2-naphthyl)-1,3-thiazol- 2-yl)amino)phenol