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1-(5-fluoropentyl)-3-(1-naphthoyl)indole

a cannabimimetic; structure in first source

Also Known As:

1-((5-fluoropentyl)-1H-indol-3-yl)-(naphthalen-1-yl)methanone; AM-2201; AM2201

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - 1-(5-fluoropentyl)-3-(1-naphthoyl)indole: 5

Experts

1.	Baumann, Michael H: 1 article (12/2018)
2.	Carlier, Jeremy: 1 article (12/2018)
3.	Huestis, Marilyn A: 1 article (12/2018)
4.	Salmeron, Bonita D: 1 article (12/2018)
5.	Scheidweiler, Karl B: 1 article (12/2018)
6.	Wohlfarth, Ariane: 1 article (12/2018)
7.	Funada, Masahiko: 1 article (01/2018)
8.	Takebayashi-Ohsawa, Mika: 1 article (01/2018)
9.	Hess, C: 1 article (12/2015)
10.	Kernbach-Wighton, G: 1 article (12/2015)

Related Diseases

1.	Cognitive Dysfunction 10/01/2013 - "Synthetic cannabinoid testing was performed by LC-MS-MS. Positive results included: JWH-018 (n = 4), 0.1-1.1 ng/mL; JWH-081 (n = 2) qualitative only; JWH-122 (n = 3), 2.5 ng/mL; JWH-210 (n = 4), 0.1 ng/mL; JWH-250 (n = 1), 0.38 ng/mL and AM-2201 (n = 6), 0.43-4.0 ng/mL. While there is good evidence of psychophysical impairment in these subjects, further structured data collection is needed to fully assess the relationship between synthetic cannabinoid use and psychomotor and cognitive impairment. "
2.	Stab Wounds (Stab Wound) 11/01/2013 - "A statewide surveillance system identified a fatality involving a 23-year-old man found with a large stab wound to the neck following use of a SC product suspected of containing AM2201. "
3.	Seizures (Absence Seizure) 01/01/2018 - "These findings are the first evidence that AM2201 induces epileptic seizures by enhancing glutamatergic transmission in the hippocampus. " 01/01/2018 - "Synthetic cannabinoid AM2201 induces seizures: Involvement of cannabinoid CB1 receptors and glutamatergic transmission."
4.	Ketosis 12/01/2015 - "In blood from a femoral vein AB-CHMINACA, AB-FUBINACA, AM-2201, 5F-AMB, 5F-APINACA, EAM-2201, JWH-018, JWH-122, MAM-2201, STS135 and THJ 2201 could be detected by LC-MS/MS. Diagnosis of ketoacidosis as cause of death was carried out using biochemical measurements of glucose and lactate concentrations in vitreous humour (sum formula: 463 mg/dl) and cerebrospinal fluid (sum formula: 506 mg/dl), of acetone (163 mg/l in femoral venous blood) and of HbA1c (98 mmol/mol). "
5.	Hypothermia 12/01/2018 - "We found that AM-2201 produced dose-related hypothermia and catalepsy that peaked at 2 hours and lasted up to 8 hours. "

Related Drugs and Biologics

1.	Cannabinoids
2.	(4- methyl- 1- naphthyl)- (1- pentylindol- 3- yl)methanone
3.	1-pentyl-3-(1-naphthoyl)indole
4.	4- ethylnaphthalen- 1- yl- (1- pentylindol- 3- yl)methanone
5.	1-(1- pentyl- 1H- indol- 3- yl)- 2- (2- methoxyphenyl)ethanone
6.	(4- methoxy- 1- naphthalenyl)(1- pentyl- 1H- indol- 3- yl)methanone
7.	Lactic Acid (Lactate)
8.	Glucose (Dextrose)
9.	Acetone
10.	AB-FUBINACA