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N-acetylaspartyl-beta-linked glutamate

antagonizes action of both NAAG and LY379268

Also Known As:

beta-NAAG

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - N-acetylaspartyl-beta-linked glutamate: 1

Experts

1.	Durden, Anna V: 1 article (11/2003)
2.	Koenig, Michael L: 1 article (11/2003)
3.	Long, Joseph B: 1 article (11/2003)
4.	Yourick, Debra L: 1 article (11/2003)

Related Diseases

1.	Hypoxia (Hypoxemia) 11/21/2003 - "Since NAAG has been shown to have neuroprotective characteristics in a number of experimental preparations, it is the purpose of the present study to specifically evaluate the possible efficacy of NAAG and beta-NAAG against NMDA- and hypoxia-induced injury to spinal cord mixed neuronal and glial cell cultures. " 11/21/2003 - "NAAG (500-1000 microM) protected against NMDA- or hypoxia-induced injuries to spinal cord cultures, and the nonhydrolyzable analog beta-NAAG (250-1000 microM) completely eliminated the loss of viability caused by either insult. " 11/21/2003 - "N-acetylaspartylglutamate and beta-NAAG protect against injury induced by NMDA and hypoxia in primary spinal cord cultures."
2.	Wounds and Injuries (Trauma) 11/21/2003 - "NAAG (500-1000 microM) protected against NMDA- or hypoxia-induced injuries to spinal cord cultures, and the nonhydrolyzable analog beta-NAAG (250-1000 microM) completely eliminated the loss of viability caused by either insult. "

Related Drugs and Biologics

1.	N-Methylaspartate (NMDA)
2.	isospaglumic acid (NAAGA)