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SCH 900229

structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - SCH 900229: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - SCH 900229: 3
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfones: 534
    - SCH 900229: 3

Experts

1.	Burnett, Duane A: 3 articles (12/2016 - 11/2012)
2.	Clader, John: 3 articles (12/2016 - 11/2012)
3.	Cohen-Williams, Mary E: 3 articles (12/2016 - 11/2012)
4.	Del Vecchio, Robert A: 3 articles (12/2016 - 11/2012)
5.	Greenlee, William J: 3 articles (12/2016 - 11/2012)
6.	Hyde, Lynn A: 3 articles (12/2016 - 11/2012)
7.	Lee, Julie: 3 articles (12/2016 - 11/2012)
8.	Nomeir, Amin: 3 articles (12/2016 - 11/2012)
9.	Parker, Eric M: 3 articles (12/2016 - 11/2012)
10.	Song, Lixin: 3 articles (12/2016 - 11/2012)

Related Diseases

1.

Alzheimer Disease (Alzheimer's Disease)

12/01/2016 - "In this paper we describe our strategy to improve the aqueous solubility of SCH 900229, a potent PS1-selective γ-secretase inhibitor for the treatment of Alzheimer's disease. "
02/01/2013 - "An investigation is detailed of the structure activity relationships (SAR) of two sulfone side chains of compound (-)-1a (SCH 900229), a potent, PS1-selective γ-secretase inhibitor and clinical candidate for the treatment of Alzheimer's disease. "
11/08/2012 - "Discovery of SCH 900229, a Potent Presenilin 1 Selective γ-Secretase Inhibitor for the Treatment of Alzheimer's Disease."

Related Drugs and Biologics

1.	Amyloid Precursor Protein Secretases (beta-Secretase)
2.	Presenilin-1
3.	Sulfones