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CID2950007

CDC42 protein inhibitor; structure in first source

Also Known As:

4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide; ML141 compound

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Adams, Sarah: 1 article (10/2015)
2.	Guo, Yuna: 1 article (10/2015)
3.	Hudson, Laurie G: 1 article (10/2015)
4.	Kenney, S Ray: 1 article (10/2015)
5.	Muller, Carolyn Y: 1 article (10/2015)
6.	Murray-Krezan, Cristina: 1 article (10/2015)
7.	Prekeris, Rytis: 1 article (10/2015)
8.	Romero, Elsa: 1 article (10/2015)
9.	Rutledge, Teresa: 1 article (10/2015)
10.	Sklar, Larry A: 1 article (10/2015)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 10/01/2015 - "Studies on immortalized human ovarian adenocarcinoma cells (SKOV3ip) and primary patient-derived ovarian cancer cells show that R-ketorolac is a robust inhibitor of growth factor or serum-dependent Cdc42 and Rac1 activation with a potency and cellular efficacy similar to small-molecule inhibitors of Cdc42 (CID2950007/ML141) and Rac1 (NSC23766). "
2.	Adenocarcinoma 10/01/2015 - "Studies on immortalized human ovarian adenocarcinoma cells (SKOV3ip) and primary patient-derived ovarian cancer cells show that R-ketorolac is a robust inhibitor of growth factor or serum-dependent Cdc42 and Rac1 activation with a potency and cellular efficacy similar to small-molecule inhibitors of Cdc42 (CID2950007/ML141) and Rac1 (NSC23766). "

Related Drugs and Biologics

1.	Intercellular Signaling Peptides and Proteins (Growth Factors)
2.	Ketorolac
3.	NSC 23766