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UNC1215

a probe for L3MBTL3; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Lan, Rongfeng: 1 article (12/2018)
2.	Li, Shuiming: 1 article (12/2018)
3.	Lu, Fei: 1 article (12/2018)
4.	Ma, Yue: 1 article (12/2018)
5.	Wang, Qianqian: 1 article (12/2018)
6.	Yu, Min: 1 article (12/2018)
7.	Zhang, Hui: 1 article (12/2018)
8.	Zhang, Xiaoming: 1 article (12/2018)
9.	Arrowsmith, Cheryl H: 1 article (03/2013)
10.	Barsyte-Lovejoy, Dalia: 1 article (03/2013)

Related Diseases

1.

Brain Neoplasms (Brain Tumor)

12/01/2018 - "In addition, PHF20L1 may regulate the stability of SOX2 through its malignant brain tumor (MBT) domain, since the degradation of SOX2 is accelerated by UNC1215 and UNC669, inhibitors that bind to the MBT domain. "
03/01/2013 - "We describe the discovery of UNC1215, a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. "

Related Drugs and Biologics

1.	Chromatin