eclalbasaponin I

has antineoplastic activity; isolated from Eclipta prostrata; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Endometrial Neoplasms (Endometrial Cancer) 09/01/2016 - "In the present study, we found that eclalbasaponin II with one glucose moiety has potent cytotoxicity in three ovarian cancer cells and two endometrial cancer cells compared to an aglycone echinocystic acid and eclalbasaponin I with two glucose moiety. "
2.	Ovarian Neoplasms (Ovarian Cancer) 09/01/2016 - "In the present study, we found that eclalbasaponin II with one glucose moiety has potent cytotoxicity in three ovarian cancer cells and two endometrial cancer cells compared to an aglycone echinocystic acid and eclalbasaponin I with two glucose moiety. "
3.	Hepatocellular Carcinoma (Hepatoma) 11/01/2012 - "The 30% ethanol fraction and eclalbasaponin I dose-dependently inhibited the proliferation of hepatoma cell smmc-7721 with IC(50) values of 74.2399 and 111.1703 μg/ml, respectively, more strongly compared with 5-fluorouracil positive control group with the IC(50) value of 195.3131 μg/ml. Antitumor activities of other fractions and compounds were lower than positive control. "