BDMC-A

08/01/2015 - "In the present study, we have investigated the inhibitory effects of BDMC-A, an analog of curcumin, on invasion, angiogenesis and metastasis markers using in vitro with MCF-7 cells and in silico studies, hence proved that BDMC-A has more potential than curcumin. "
08/01/2021 - "Our overall results revealed that BDMC-A more effectively inhibited the markers of invasion, angiogenesis and metastasis in comparison with curcumin."
08/01/2015 - "Our overall results showed that BDMC-A more effectively inhibited invasion, angiogenesis and metastasis markers compared to curcumin. "
08/01/2015 - "BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin."
01/01/2020 - "Bisdemethoxycurcumin (BDMC), a stable bioactive ingredient in curcuminoids, is associated with various antitumor functions, such as proliferation inhibition, metastasis suppression and apoptosis induction, in many cancer types. "

02/01/2003 - "Our study shows that the protective effect of BDMC-A during DMH-induced colon carcinogenesis may be due to its modulatory effects on (i). "
01/01/2005 - "We speculate that BDMC-A modulates DMH-induced oxidative stress and offers chemoprevention against colon carcinogenesis, and the modulatory effect is comparable with that of curcumin. "
01/01/2005 - "The modulating effects of a bisdemethoxycurcumin analog (BDMC-A) on 1,2-dimethylhydrazine (DMH)-induced oxidative stress during colon carcinogenesis was investigated in male Wistar rats. "
02/01/2003 - "This study was performed to study the effect of bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione, a bisdemethoxycurcumin analog (BDMC-A) on DMH-induced colon carcinogenesis in male Wistar rats and effects were compared with that of the reference drug, curcumin. "

02/01/2003 - "Our study suggest that BDMC-A may emerge as a potent anticarcinogenic agent against colon cancer. "
01/01/2005 - "Thus, lipid peroxidation and antioxidant status together could be used as markers of colon cancer chemoprevention by BDMC-A."

12/01/2012 - "In this study we synthesized an analog of curcumin bis-1,7-2(hydroxyphenil)-hepta-1,6diene-3,5diore (BDMC-A) and investigated its anti-breast cancer property. "
12/01/2012 - "We compared the impact of bis-1,7-2(hydroxyphenil)-hepta-1,6diene-3,5diore (BDMC-A) with that of curcumin in human breast cancer cell line MCF-7. "
08/01/2015 - "BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin."

12/01/2022 - "Bisdemethoxycurcumin (BDMC), a natural product, was obtained from the rhizome of turmeric (Curcuma longa) and exerts antitumor activities in numerous human cancer cell lines. "
10/01/2022 - "Bisdemethoxycurcumin (BDMC), a natural product, was isolated from the rhizome of turmeric (Curcuma longa), which has been shown to against many human cancer cells. "
01/01/2005 - "In groups of animals given DMH and BDMC-A no tumors were observed, and the lipid peroxidation as well as the GSH-dependent enzymes showed a pattern similar to that of untreated control rats. "
01/01/2020 - "Bisdemethoxycurcumin (BDMC), a stable bioactive ingredient in curcuminoids, is associated with various antitumor functions, such as proliferation inhibition, metastasis suppression and apoptosis induction, in many cancer types. "
08/01/2021 - "The results showed that BDMC-A inhibits the transcription factors NF-κB, p65, c-Jun, c-Fos, STAT3, STAT5, PPAR-γ and β-catenin, which are responsible for tumor progression and malignancy. "