6-OH-BDE-47

hydroxylated BDE-47 metabolite; BDE - bromobiphenyl ether

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 04/01/2020 - "However, as a potential neurotoxin, whether 6-OH-BDE-47 could promote the development of typical neurodegenerative diseases such as Parkinson's disease (PD) is still unknown. "
2.	Parkinson Disease (Parkinson's Disease) 04/01/2020 - "6-OH-BDE-47 exposure-induced Parkinson's disease pathology in Sprague Dawley rat." 04/01/2020 - "However, as a potential neurotoxin, whether 6-OH-BDE-47 could promote the development of typical neurodegenerative diseases such as Parkinson's disease (PD) is still unknown. "
3.	Lung Neoplasms (Lung Cancer) 01/01/2015 - "Generally, our results revealed for the first time that 6-OH-BDE-47 promoted the EMT of lung cancer cells via AKT/Snail signals. " 01/01/2015 - "6-OH-BDE-47 promotes human lung cancer cells epithelial mesenchymal transition via the AKT/Snail signal pathway."
4.	Herpes Zoster 01/01/2015 - "This was confirmed by that 6-OH-BDE-47 significantly down regulated the expression of epithelial markers E-cadherin (E-Cad) and zona occludin-1 (ZO-1) while up regulated the mesenchymal markers vimentin (Vim) and N-cadherin (N-Cad). "
5.	Glioma (Gliomas) 06/15/2015 - "BDE-99 decreased DIO2 activity by 50% in primary astrocyte cells and by up to 80% in the H4 cells at doses of ≥500 nM. 3-OH-BDE-47, 6-OH-BDE-47, and 5'-OH-BDE-99 also decreased DIO2 activity in cultured H4 glioma cells by 45-80% at doses of approximately 1-5 μM. "