X-Linked Infantile Nystagmus

02/01/1991 - "Passive transfer of Navy yoelii sporozoite 1 (NYS1), an IgG3 mAb against the P. "
01/01/1990 - "In contrast, we tested sera from mice that received NYS1, an IgG3 MAb, in passive transfer and were protected against challenge with 5000 sporozoites. "
01/01/1990 - "Passive transfer of NYS1, an IgG3 MAb against the P. "
06/01/1993 - "These MAbs were compared tp NYS1 (IgG3), an anti-CS protein MAb previously produced by immunization with irradiated P. "
03/01/1987 - "Although NYS1 (immunoglobulin G3 [IgG3]), NYS2 (IgG3), and NYS3 (IgM) were positive in the circumsporozoite precipitation test, only NYS1 and NYS2 were able to neutralize sporozoite infectivity in mice. "

01/01/2022 - "Idiopathic infantile nystagmus (IIN) is an inherited disorder occurring in the first 6 months of life, with no underlying retinal or neurological etiologies and is predominantly caused by mutations in the FRMD7 gene. "
08/01/2017 - "To compare segmented retinal layer thicknesses between patients with idiopathic infantile nystagmus (IIN) and controls. "
08/01/2017 - "Retinal microstructures are altered in patients with idiopathic infantile nystagmus."
02/01/2014 - "There have been advances in understanding mechanisms underlying idiopathic infantile nystagmus, which has progressed through determining the role of the FRMD7 gene in controlling neurite outgrowth, and albinism, in which recent models have investigated the possibility of retinal miswiring leading to nystagmus. "
10/01/2017 - "The main types of nystagmus, in declining order, were nystagmus associated with retinal/optic nerve disease in 23 (32.4%), idiopathic or congenital motor nystagmus in 22 (31.0%), manifest latent nystagmus or latent nystagmus in 17 (24.0%), and 2 (2.8%) each associated with Chiari malformation, medication use, tumor of the central nervous system, and no diagnosis. "

05/15/2013 - "Idiopathic infantile nystagmus (IIN) is a genetically heterogeneous disorder of eye movement that can be caused by mutations in the FRMD7 gene that encodes a FERM domain protein. "
01/15/2010 - "Mutations in the gene encoding FERM domain-containing 7 protein (FRMD7) are recognized as an important cause of X-linked idiopathic infantile nystagmus (IIN). "
06/01/1993 - "These MAbs were compared tp NYS1 (IgG3), an anti-CS protein MAb previously produced by immunization with irradiated P. "

02/01/1991 - "The levels of antibodies to (QGPGAP)2 by ELISA, and to sporozoites by indirect fluorescent antibody test and CS precipitation reaction were similar in sera from mice that received NYS1 in passive transfer and were protected against challenge with 5000 sporozoites, and from mice that had been immunized with subunit vaccines containing (QGPGAP)2 but were not protected against challenge with 40-200 sporozoites. "
01/01/1990 - "The levels of antibodies to (QGPGAP)2 by ELISA, and to sporozoites by IFAT and CS precipitation reaction were similar in sera from mice that received NYS1 in passive transfer and were protected against challenge with 5000 sporozoites, and from mice that had been immunized with subunit vaccines containing QGPGAP but were not protected against challenge with 40-200 sporozoites. "

02/01/1991 - "The results suggest that NYS1, the protective mAb, has a lower avidity for (QGPGAP)2 and for sporozoites than do the vaccine-induced antibodies. "
01/01/1990 - "The results suggest that NYS1, the protective MAb, has a lower avidity for (QGPGAP)2 and for sporozoites than do the vaccine-induced antibodies. "

07/01/1985 - "Double mutants nys1 nysX are characterized by a "mixed" UV spectra of sterols."
10/01/1971 - "Conversion of nys(+) and nys3 to petite results in loss of 24(28)-dehydroergosterol in the former and the new sterol in the latter, whereas the new sterol in nys1 is only reduced. "
10/01/1971 - "In nys1 mutants, the spectrum suggests the presence of a new sterol. "
10/01/1971 - "Mutants of the genes nys1 and nys3 differ from sensitive strains (nys(+)) in their sterol content. "

02/01/1991 - "Binding of NYS1 to sporozoites was inhibited by incubation with (QGPGAP)2, a synthetic peptide derived from the repeat region of the P. "
01/01/1990 - "Binding of NYS1 to sporozoites was inhibited by incubation with (QGPGAP)2, indicating that the epitope on sporozoites recognized by this MAb was included within this peptide. "

01/01/1990 - "MAbs NYS1, NYS2, and NYS3 recognized different epitopes of the P. "
01/01/1990 - "Binding of NYS1 to sporozoites was inhibited by incubation with (QGPGAP)2, indicating that the epitope on sporozoites recognized by this MAb was included within this peptide. "

02/01/1991 - "The results suggest that NYS1, the protective mAb, has a lower avidity for (QGPGAP)2 and for sporozoites than do the vaccine-induced antibodies. "
02/01/1991 - "The levels of antibodies to (QGPGAP)2 by ELISA, and to sporozoites by indirect fluorescent antibody test and CS precipitation reaction were similar in sera from mice that received NYS1 in passive transfer and were protected against challenge with 5000 sporozoites, and from mice that had been immunized with subunit vaccines containing (QGPGAP)2 but were not protected against challenge with 40-200 sporozoites. "
01/01/1990 - "The results suggest that NYS1, the protective MAb, has a lower avidity for (QGPGAP)2 and for sporozoites than do the vaccine-induced antibodies. "
01/01/1990 - "The levels of antibodies to (QGPGAP)2 by ELISA, and to sporozoites by IFAT and CS precipitation reaction were similar in sera from mice that received NYS1 in passive transfer and were protected against challenge with 5000 sporozoites, and from mice that had been immunized with subunit vaccines containing QGPGAP but were not protected against challenge with 40-200 sporozoites. "

11/01/2016 - "A previously unidentified deletion in G protein-coupled receptor 143 causing X-linked congenital nystagmus in a Chinese family."

01/01/2011 - "An augmented Anderson procedure combined with tenotomy and reattachment of the remaining horizontal rectus muscles is safe and effective in reducing both abnormal compensatory head posture and nystagmus in idiopathic infantile nystagmus with minimal risk of overcorrection."
01/01/2011 - "To evaluate the effectiveness of an augmented Anderson procedure combined with tenotomy and reattachment of the remaining horizontal rectus muscles in correcting horizontal compensatory head posture associated with idiopathic infantile nystagmus. "

08/01/2017 - "Slit lamp photography of the anterior segment, fundus photography, optical coherence tomography and electroretinogram were carried out to identify the clinical features of congenital motor nystagmus. "

05/01/1991 - "X-linked congenital nystagmus is a rare disorder in which affected males manifest binocular uniplanar nystagmus with associated head oscillation. "

03/01/2002 - "We report the results of laser in situ keratomileusis (LASIK) to correct myopia in a 47-year-old woman with congenital motor nystagmus and myopia. "

01/01/2020 - "Electroretinogram amplitudes in idiopathic infantile nystagmus group showed increased white scotopic and photopic electroretinograms in 26 children (skin electrode to Great Ormond Street Hospital protocol), no difference to the controls in 3 children (skin electrode to International Society for Clinical Electrophysiology of Vision protocol), and increased rod electroretinogram in 3 children (HK electrode to International Society for Clinical Electrophysiology of Vision protocol). "