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Fcy-hEGF fusion protein

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Gastrointestinal Hormones: 573
    - Epidermal Growth Factor: 13752
      - Fcy-hEGF fusion protein: 2
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - EGF Family of Proteins: 90
      - Epidermal Growth Factor: 13752
        Fcy-hEGF fusion protein: 2
  - Recombinant Proteins: 2754
    - Recombinant Fusion Proteins: 333
      - Fcy-hEGF fusion protein: 2
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - EGF Family of Proteins: 90
      - Epidermal Growth Factor: 13752
        Fcy-hEGF fusion protein: 2
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - EGF Family of Proteins: 90
    - Epidermal Growth Factor: 13752
      - Fcy-hEGF fusion protein: 2
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Aminohydrolases: 1
      - Nucleoside Deaminases
        Cytosine Deaminase: 481
        Fcy-hEGF fusion protein: 2

Experts

1.	Lan, Keng-Li: 2 articles (02/2021 - 11/2012)
2.	Chang, Chih-Hsien: 1 article (02/2021)
3.	Cheng, Chu-Nian: 1 article (02/2021)
4.	Hsu, Wei-Chuan: 1 article (02/2021)
5.	Huang, Yi-Shu: 1 article (02/2021)
6.	Lee, Te-Wei: 1 article (02/2021)
7.	Lin, Chien-Hong: 1 article (02/2021)
8.	Lin, Ming-Syuan: 1 article (02/2021)
9.	Lo, Sheng-Nan: 1 article (02/2021)
10.	Chang, Cheng Allen: 1 article (11/2012)

Related Diseases

1.

Neoplasms (Cancer)

11/16/2012 - "5-Fluorocytosine combined with Fcy-hEGF fusion protein targets EGFR-expressing cancer cells."
02/14/2021 - "Fcy-hEGF fusion protein, composed of yeast cytosine deaminase (Fcy) and human EGF (hEGF), is capable of binding to EGFR and enzymatically convert 5-fluorocytosine (5-FC) to 1000-fold toxic 5-fluorocuracil (5-FU), thereby inhibiting the growth of EGFR-expressing tumor cells. "

Related Drugs and Biologics

1.	Flucytosine (Ancobon)
2.	Cytosine Deaminase
3.	Epidermal Growth Factor (EGF)