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pyrazine-2-carboxylic acid N'- (7- fluoropyrrolo(1,2- a)quinoxalin- 4- yl)- hydrazide

has antineoplastic activity; structure in first source

Also Known As:

NVX-412

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrazines: 379
  - pyrazine-2-carboxylic acid N'- (7-fluoropyrrolo(1,2-a)quinoxalin-4-yl)-hydrazide: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinoxalines: 324
      - pyrazine-2-carboxylic acid N'- (7-fluoropyrrolo(1,2-a)quinoxalin-4-yl)-hydrazide: 1

Experts

1.	Hebar, Alexandra: 1 article (01/2012)
2.	Rütgen, Barbara C: 1 article (01/2012)
3.	Selzer, Edgar: 1 article (01/2012)

Related Diseases

1.	Hematologic Neoplasms (Hematological Malignancy) 01/01/2012 - "Based on the broad and consistent anti-neoplastic activity observed, NVX-412 holds promise as an effective drug candidate for the treatment of various cancer types, especially for hematological malignancies with highly unmet medical need."
2.	Neoplasms (Cancer) 01/01/2012 - "The new molecular entity quinoxalinhydrazide derivative NVX-412 was identified as a promising drug candidate for the treatment of various cancer types due to its strong cytotoxic activity and relative specificity. " 01/01/2012 - "NVX-412, a new oncology drug candidate, induces S-phase arrest and DNA damage in cancer cells in a p53-independent manner." 01/01/2012 - "Based on the broad and consistent anti-neoplastic activity observed, NVX-412 holds promise as an effective drug candidate for the treatment of various cancer types, especially for hematological malignancies with highly unmet medical need."