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(7- (2- ((1,1'- biphenyl)- 4- ylmethylene)hydrazinyl)- N- hydroxy- 7- oxoheptanamide)

structure in first source

Also Known As:

crebinostat

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        (7-(2-((1,1'-biphenyl)-4-ylmethylene)hydrazinyl)-N-hydroxy-7-oxoheptanamide): 1
- Hydrazines: 379
  - (7-(2-((1,1'-biphenyl)-4-ylmethylene)hydrazinyl)-N-hydroxy-7-oxoheptanamide): 1

Experts

1.	Barker, Douglas D: 1 article (01/2013)
2.	Fass, Daniel M: 1 article (01/2013)
3.	Ghosh, Balaram: 1 article (01/2013)
4.	Guan, Ji-Song: 1 article (01/2013)
5.	Haggarty, Stephen J: 1 article (01/2013)
6.	Hennig, Krista M: 1 article (01/2013)
7.	Joseph, Nadine F: 1 article (01/2013)
8.	Kuhnle, Chelsea E Groves: 1 article (01/2013)
9.	Mazitschek, Ralph: 1 article (01/2013)
10.	Nieland, Thomas J F: 1 article (01/2013)

Related Diseases

1.

Cognitive Dysfunction

01/01/2013 - "Taken together, these results demonstrate that crebinostat provides a novel probe to modulate chromatin-mediated neuroplasticity and further suggests that pharmacological optimization of selective of HDAC inhibitors may provide an effective therapeutic approach for human cognitive disorders. "
01/01/2013 - "Finally, crebinostat treatment of cultured mouse primary neurons was found to upregulate Bdnf (brain-derived neurotrophic factor) and Grn (granulin) and downregulate Mapt (tau) gene expression-genes implicated in aging-related cognitive decline and cognitive disorders. "

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