human pituitary tumor-transforming protein 1

PTTG - pituitary tumor transforming gene; RefSeq NM_004219

Also Known As:

pituitary tumor-transforming protein 1, human; EAP1 protein, human; PTTG protein, human; PTTG1 protein, human; TUTR1 protein, human; enhanced at puberty 1 protein, human; hPTTG protein; hPTTG1 protein; pituitary tumor-transforming 1 protein, human; securin, human

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Cell Cycle Proteins: 807
    - Securin: 135
      - human pituitary tumor-transforming protein 1: 4

Experts

1.	Cheng, Ye-Xia: 1 article (09/2004)
2.	Feng, Jie: 1 article (09/2004)
3.	Fu, Tian-Yun: 1 article (09/2004)
4.	Yao, Yu: 1 article (09/2004)
5.	Zhang, Xin-Yan: 1 article (09/2004)
6.	Domínguez, A: 1 article (01/2000)
7.	Luna, R: 1 article (01/2000)
8.	Multon, M C: 1 article (01/2000)
9.	Pintor-Toro, J A: 1 article (01/2000)
10.	Ramos-Morales, F: 1 article (01/2000)

Related Diseases

1.	Starvation 01/20/2000 - "hPTTG protein level is up-regulated in rapidly proliferating cells, is down-regulated in response to serum starvation or cell confluence, and is regulated in a cell cycle-dependent manner, peaking in mitosis. "
2.	Pituitary Neoplasms (Pituitary Adenoma) 03/01/1999 - "hPTTG is highly expressed in cancer cell lines, pituitary adenomas and in normal testis, suggesting that hPTTG protein has different tissue-specific interactions in normal cells and in cancer. "
3.	Neoplasms (Cancer) 03/01/1999 - "hPTTG is highly expressed in cancer cell lines, pituitary adenomas and in normal testis, suggesting that hPTTG protein has different tissue-specific interactions in normal cells and in cancer. "
4.	Carcinoma (Carcinomatosis) 09/01/2004 - "HPTTG1 protein was expressed in all cases of ovarian carcinoma, but not in normal ovaries. " 09/01/2004 - "HPTTG1 mRNA expression in 27 cases of epithelial human ovarian carcinoma, and 4 cases of normal ovary was assessed with non-competitive reverse transcription polymerase chain reaction (RT-PCR), and hPTTG1 protein expression in these 27 cases of human ovarian carcinoma, and 18 cases of normal ovary was examined by immunohistochemistry. "
5.	Adenoma (Adenomas) 09/23/1999 - "hPTTG protein was immunolocalized mainly in the cytoplasm of adenoma cells. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)