VU0409106

a metabotropic glutamate receptor 5 antagonist; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Obesity 01/01/2021 - "Herein, we evaluated the effect of VU0409106, a negative allosteric modulator (NAM) of mGluR5 in regulating feeding and obesity parameters. "
2.	Inflammation (Inflammations) 01/01/2021 - "Our data suggest reduction of feeding, body weight, and adipose tissue inflammation in mice treated with high-fat diet (HFD) after chronic treatment with VU0409106. "
3.	Body Weight (Weight, Body) 01/01/2021 - "Diet-induced obese C57BL/6 mice were treated for 14 days with VU0409106, and food intake, body weight, inflammatory/hormonal levels, and behavioral tests were performed. " 01/01/2021 - "Our data suggest reduction of feeding, body weight, and adipose tissue inflammation in mice treated with high-fat diet (HFD) after chronic treatment with VU0409106. "