IR-786

11/09/2022 - "Additional in vivo studies using mouse tumor models revealed that BF800-AM targeting to BAT is independent of tumor tissues, as distinct from IR-786 showing uptake in both tissues. "
03/19/2022 - "Owing to the poor tumor specificity of IR-786 itself, in vivo studies on tumor-targeted imaging have not yet been investigated. "
01/03/2023 - "Moreover, IR-786 bound to BSA played an important role in tumor growth suppression due to its cytotoxicity. "
03/19/2022 - "Thus, IR-786 should be designed to be more soluble in aqueous solutions so that it can preferentially accumulate in the tumor based on the structure-inherent targeting strategy. "
03/19/2022 - "A tumor-targeted near-infrared (NIR) fluorophore CA800Cl was developed based on commercially available IR-786 by modulating its physicochemical properties. "