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acetyl-glucagon-like peptide 1 (7-34)-amide

Also Known As:

Ac-GLP-1-(7-34)-amide; curaglutide

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Fragments: 373
    - acetyl-glucagon-like peptide 1 (7-34)-amide: 2
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Gastrointestinal Hormones: 573
    - Proglucagon: 128
      - Glucagon-Like Peptides: 424
        Glucagon-Like Peptide 1: 6089
        acetyl-glucagon-like peptide 1 (7-34)-amide: 2

Experts

1.	Döhler, Klaus D: 1 article (10/2012)
2.	Engstrøm, Thomas: 1 article (10/2012)
3.	Salling, Henrik K: 1 article (10/2012)
4.	Treiman, Marek: 1 article (10/2012)
5.	Adermann, Knut: 1 article (02/2008)
6.	Forssmann, Wolf-Georg: 1 article (02/2008)
7.	John, Harald: 1 article (02/2008)
8.	Maronde, Erik: 1 article (02/2008)
9.	Meyer, Markus: 1 article (02/2008)

Related Diseases

1.	Reperfusion Injury 10/10/2012 - "Curaglutide is a new, proteolysis-resistant GLP-1 analog with a beneficial effect on reperfusion-injury in an isolated rat heart. " 10/10/2012 - "Postconditioning with curaglutide, a novel GLP-1 analog, protects against heart ischemia-reperfusion injury in an isolated rat heart."
2.	Ischemia 10/10/2012 - "Curaglutide did not affect any of the functional heart parameters when administered without preceding ischemia. "
3.	Insulinoma 02/25/2008 - "Ac-GLP-1-(7-34)-amide induced a concentration-dependent increase of intracellular cAMP production and insulin release from rat insulinoma RIN-m5F cells to an extent comparable to that found for the N-terminally unblocked peptides GLP-1-(7-34)-amide and GLP-1-(7-36)-amide. "
4.	Infarction (Infarctions) 10/10/2012 - "Infarct size was reduced by curaglutide postconditioning from 24.8% (SEM 2.8, N=14) to 11.4% (SEM 3.2, N=8; P<0.05). " 10/10/2012 - "These effects of curaglutide on postischemic hypercontracture and infarct size were similar in magnitude to corresponding effects of GLP-1 receptor agonist exendin-4. "

Related Drugs and Biologics

1.	Glucagon-Like Peptide 1 (GLP 1)
2.	Peptides (Polypeptides)
3.	Insulin (Novolin)
4.	Exenatide (Byetta)
5.	Glucagon-Like Peptide-1 Receptor