HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
1- (9- deazaadenin- 9- yl)methyl- 3- hydroxy- 4- methylthiomethylpyrrolidine
inhibits both methylthioadenosine phosphorylase and methylthioadenosine-S-adenosylhomocysteine nucleosidase; structure in first source
Also Known As:
MT-DADMe-immucillin-A
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrrolidines: 115
1-(9-deazaadenin-9-yl)methyl-3-hydroxy-4-methylthiomethylpyrrolidine: 1
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleosides: 360
Adenosine: 12431
1-(9-deazaadenin-9-yl)methyl-3-hydroxy-4-methylthiomethylpyrrolidine: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Purine Nucleosides: 360
Adenosine: 12431
1-(9-deazaadenin-9-yl)methyl-3-hydroxy-4-methylthiomethylpyrrolidine: 1
Ribonucleosides: 49
Adenosine: 12431
1-(9-deazaadenin-9-yl)methyl-3-hydroxy-4-methylthiomethylpyrrolidine: 1
Experts
1.
Chattopadhyay, Shrikanta
: 1 article (10/2006)
2.
Goldman, I David
: 1 article (10/2006)
3.
Schramm, Vern L
: 1 article (10/2006)
4.
Tsai, Eugenia
: 1 article (10/2006)
5.
Zhao, Rongbao
: 1 article (10/2006)
Related Diseases
1.
Mesothelioma
10/01/2006 - "
The current study addresses the effect of MTAP on pemetrexed activity using a highly potent transition state inhibitor of MTAP, MT-DADMe-Immucillin A (ImmA; K(i) = 86 pmol/L) in the MTAP(+) NCI-H28 and MTAP(-) NCI-H2052 mesothelioma cell lines.
"
Related Drugs and Biologics
1.
Pemetrexed (MTA)