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protein kinase C gamma (141-151)

Also Known As:

C1B5 peptide

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - Protein Kinase C: 5856
        protein kinase C gamma (141-151): 2
- Peptides: 82426
  - Peptide Fragments: 373
    - protein kinase C gamma (141-151): 2
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        Protein Kinase C: 5856
        protein kinase C gamma (141-151): 2

Experts

1.	Kawabata, Atsushi: 2 articles (01/2018 - 08/2012)
2.	Tamura, Masaaki: 2 articles (01/2018 - 08/2012)
3.	Inui, Makoto: 1 article (01/2018)
4.	Ishiguro, Susumu: 1 article (01/2018)
5.	Monson, Kelsey: 1 article (01/2018)
6.	Ohta, Naomi: 1 article (01/2018)
7.	Pappas, Charalampos G: 1 article (01/2018)
8.	Tzakos, Andreas G: 1 article (01/2018)
9.	Uppalapati, Deepthi: 1 article (01/2018)
10.	Zulbaran-Rojas, Alejandro: 1 article (01/2018)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 01/01/2018 - "Two- and three-dimensional cell culture studies clarified that a co-treatment with C1B5 peptide and gemcitabine significantly attenuated growth of PAN02 mouse and PANC-1 human pancreatic cancer cells in 2D and 3D cultures. " 01/01/2018 - "Co-treatment with a C1B5 peptide of protein kinase Cγ and a low dose of gemcitabine strongly attenuated pancreatic cancer growth in mice through T cell activation."
2.	Neoplasms (Cancer) 01/01/2018 - "Although treatment with the low dose of gemcitabine alone (76%) or the C1B5 peptide alone (39%) inhibited tumor growth moderately, a co-treatment with C1B5 peptide and a low dose of gemcitabine markedly inhibited the growth of PAN02 autografts in the mouse peritoneal cavity (94% inhibition) without any noticeable adverse effect. " 08/01/2012 - "Sub-micromolar to micromolar levels of both C1B peptides induced approximately 60-70% growth attenuation in multiple colon cancer cell lines in a soft agar tumor colony assay; however, C1B5 peptide was not cytotoxic to normal colon epithelial cells in two dimensional culture. "
3.	Colonic Neoplasms (Colon Cancer) 08/01/2012 - "Sub-micromolar to micromolar levels of both C1B peptides induced approximately 60-70% growth attenuation in multiple colon cancer cell lines in a soft agar tumor colony assay; however, C1B5 peptide was not cytotoxic to normal colon epithelial cells in two dimensional culture. "

Related Drugs and Biologics

1.	Gemcitabine
2.	Protein Kinases (Protein Kinase)
3.	Peptides (Polypeptides)
4.	Agar