cypate-2DG
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1 trials/studies)
Bio-Agent Context: Research Results
Experts
Related Diseases
| 1. | Neoplasms (Cancer)
05/01/2012
- " The results show that both Cypate-2DG and ICG-Der-02-2DG possess tumor targeting ability on all the tumors examined, with a proportional correlation to GLUT1 expression. " 05/01/2012
- " Cypate-2DG had slower but stronger tumor targeting ability compared with ICG-Der-02-2DG. " 05/01/2012
- " To investigate the correlation between the targeting ability of the probe and the glucose transporter (GLUT1) expression levels of cancer cells, the accumulation of Cypate-2DG in tumors was assessed in MCF-7/estradiol, U87MG, MCF-7 and MDA-MB-435 tumor xenografts, which express different levels of GLUT1. " 05/01/2012
- " In this study, two near-infrared fluorescent dyes, Cypate and ICG-Der-02, with different water solubility, were conjugated to 2-amino-2-deoxy-D-glucose (2DG) to form Cypate-2DG and ICG-Der-02-2DG, respectively, for NIR fluorescent imaging of tumors in nude mice. "
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