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(4- chlorophenyl)- (1H- imidazol- 4- ylmethyl)- isopropyl- amine

a TAAR1 partial antagonist; structure in first source

Also Known As:

RO5073012

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - (4-chlorophenyl)-(1H-imidazol-4-ylmethyl)-isopropyl-amine: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - (4-chlorophenyl)-(1H-imidazol-4-ylmethyl)-isopropyl-amine: 2

Experts

1.	Li, Jun-Xu: 1 article (12/2021)
2.	Wu, Ruyan: 1 article (12/2021)
3.	Galley, Guido: 1 article (08/2012)
4.	Goergler, Annick: 1 article (08/2012)
5.	Hoener, Marius C: 1 article (08/2012)
6.	Norcross, Roger D: 1 article (08/2012)
7.	Stalder, Henri: 1 article (08/2012)

Related Diseases

1.	Substance-Related Disorders (Drug Abuse) 12/01/2021 - "Selective and potent engineered TAAR1 ligands, including full (RO5166017 and RO5256390) and partial (RO5203648, RO5263397 and RO5073012) agonists and the antagonist EPPTB (N-(3-ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl) benzamide, RO5212773), serve as invaluable tools for the investigation of TAAR1 functions and display significant potential for the development of TAAR1-based pharmacotherapies for the treatment of substance use disorders. "
2.	Schizophrenia (Dementia Praecox) 08/15/2012 - "RO5073012 has been found to be active in a behavioural rat model which is considered indicative for schizophrenia."

Related Drugs and Biologics

1.	Ligands
2.	RO5166017
3.	4- (3,4- dichlorophenyl)- 4,5- dihydrooxazol- 2- ylamine
4.	RO5256390
5.	4- (3- fluoro- 2- methylphenyl)- 4,5- dihydrooxazol- 2- ylamine

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)