ponceau 4R (E 124)

structure in first source

Also Known As:

E 124; cochineal red A; 1,3-naphthalenedisulfonic acid, 7-hydroxy-8-((4-sulfo-1-naphthalenyl azo) trisodium salt); 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulfonate; Acid Red-18; C.I. food red 16255; Scarlet-3R; cochineal red; new coccine

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Anderl-Straub, Sarah: 1 article (01/2022)
2.	Danek, Adrian: 1 article (01/2022)
3.	Diehl-Schmid, Janine: 1 article (01/2022)
4.	Egger, Karl: 1 article (01/2022)
5.	FTLD-Consortium Germany: 1 article (01/2022)
6.	Fassbender, Klaus: 1 article (01/2022)
7.	Fliessbach, Klaus: 1 article (01/2022)
8.	German Atypical Parkinson Consortium Study Group: 1 article (01/2022)
9.	Hattingen, Elke: 1 article (01/2022)
10.	Hilker-Roggendorf, Rüdiger: 1 article (01/2022)

Related Diseases

1.	Immediate Hypersensitivity 11/01/2014 - "This study reports an unusual case of IgE-mediated hypersensitivity to Cochineal red or Carmine red, a coloring agent of natural origin. "
2.	Hypersensitivity (Allergy) 11/01/2014 - "New risks from ancient food dyes: cochineal red allergy." 09/01/1995 - "[Hypersensitivity to Sintrom, caused by cochineal red A]." 10/01/2020 - "The most threatening as to the development of allergic reactions in children (dermatitis, urticaria) are the following additives: E 102 - tartrazine, E 103 - alkaline, E 104 - yellow quinoline, E 105 - transparent yellow, E 110 - yellow "sunset", E 111 - orange alpha-naphthol, E 122 - carmoazine, E 123 - amaranth, E 124 - ponso 4R, E 126 - ponso 6R. "
3.	Body Weight (Weight, Body) 10/01/2006 - "Nevertheless, the middle-dose and high-dose levels were in excess of the acceptable daily intake (ADI) of Ponceau 4R (0-4.0mg/kg body weight), and the actual dietary intake of Ponceau 4R in humans is presumed to be much lower. " 12/01/1987 - "It is concluded that the no-adverse-effect level for Ponceau 4R is 1250 mg/kg body weight/day." 12/01/1987 - "Ponceau 4R was fed to three generations of rats, at dietary concentrations to provide 0, 50, 500 or 1250 mg/kg body weight/day. " 12/01/1987 - "Groups of 66 (treated) or 114 (control) rats of each sex were fed diets providing 0 (control), 50, 500 or 1250 mg Ponceau 4R/kg body weight/day for 60 days. "
4.	Urticaria (Hives) 10/01/2020 - "The most threatening as to the development of allergic reactions in children (dermatitis, urticaria) are the following additives: E 102 - tartrazine, E 103 - alkaline, E 104 - yellow quinoline, E 105 - transparent yellow, E 110 - yellow "sunset", E 111 - orange alpha-naphthol, E 122 - carmoazine, E 123 - amaranth, E 124 - ponso 4R, E 126 - ponso 6R. " 10/01/2022 - "Patients suspected of urticaria exacerbations after ingestion of azo dyes were enrolled in a placebo-controlled single-blind oral challenge (OC) with a mixture of azo food dyes: tartrazine, Quinoline Yellow, Sunset Yellow, Cochineal Red, Allura Red, and azorubine. "
5.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2022 - "Atlas-based volumetry was performed on multi-centric T1-weighted MRI data from 940 subjects, i.e., 124 healthy controls and 816 patients with ten different neurodegenerative diseases, leading to a multi-diagnostic multi-class classification task with eleven different classes. "

Related Drugs and Biologics

1.	Coloring Agents (Dyes)
2.	Carmine (Natural Red 4)
3.	Tartrazine
4.	Azo Compounds
5.	6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt (Sunset yellow FCF)
6.	Wastewater
7.	beta Carotene (Betacarotene)
8.	Acenocoumarol
9.	quinoline
10.	1-naphthol (alpha-naphthol)