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6-OH-11-O-hydroxyphenanthrene

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Phenanthrenes: 27
        6-OH-11-O-hydroxyphenanthrene: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Phenanthrenes: 27
    - 6-OH-11-O-hydroxyphenanthrene: 4

Experts

1.	Farabegoli, Fulvia: 3 articles (08/2018 - 01/2014)
2.	Govoni, Marzia: 3 articles (08/2018 - 01/2014)
3.	Papi, Alessio: 3 articles (08/2018 - 01/2014)
4.	Spisni, Enzo: 2 articles (08/2018 - 06/2017)
5.	Ciavarella, Carmen: 1 article (01/2014)
6.	Orlandi, Marina: 1 article (01/2014)
7.	Ferreri, A M: 1 article (07/2012)
8.	Guerra, F: 1 article (07/2012)
9.	Orlandi, M: 1 article (07/2012)
10.	Papi, A: 1 article (07/2012)

Related Diseases

1.	Neuroblastoma 08/22/2018 - "Epigallocatechin-3-gallate and 6-OH-11-O-Hydroxyphenanthrene Limit BE(2)-C Neuroblastoma Cell Growth and Neurosphere Formation In Vitro." 08/22/2018 - "We conducted an in vitro study combining a rexinoid, 6-OH-11-O-hydroxyphenanthrene (IIF), and epigallocatechin-3-gallate (EGCG), which is the main catechin of green tea, on BE(2)-C, a neuroblastoma cell line representative of the high-risk group of patients. "
2.	Colonic Neoplasms (Colon Cancer) 07/01/2012 - "In this study, we investigated the antiproliferative and anti-invasive mechanism action of sodium valproate (VPA), an inhibitor of histone deacetylase (HDAC) activity, in combination with the rexinoid 6-OH-11-O-hydroxyphenanthrene (IIF), a ligand of retinoid X receptor (RXR), in the HT-29 and LoVo colon cancer cell lines. "
3.	Breast Neoplasms (Breast Cancer) 01/01/2014 - "We showed that EGCG and the rexinoid 6-OH-11-O-hydroxyphenanthrene (IIF), given together, were cytotoxic toward MCF-7, MCF-7TAM, and MDA-MB-231, three breast carcinoma cell lines showing different molecular characteristics. " 01/01/2014 - "A RXR ligand 6-OH-11-O-hydroxyphenanthrene with antitumour properties enhances (-)-epigallocatechin-3-gallate activity in three human breast carcinoma cell lines." 06/30/2017 - "We investigated the effects of epigallocatechin-3-gallate (EGCG), the most active green tea catechin, in combination with 6-OH-11-O-hydroxyphenanthrene (IIF), a synthetic retinoid X receptor-γ (RXRγ) agonist, on three breast carcinoma cell lines: MCF-7, MCF-7TAM and MDA-MB-231. "

Related Drugs and Biologics

1.	Retinoid X Receptors (Retinoid X Receptor)
2.	Tea
3.	Ligands
4.	Catechin (Z 7300)
5.	epigallocatechin gallate (epigallocatechin-3-gallate)
6.	Valproic Acid (Depakote)
7.	Histone Deacetylases (Histone Deacetylase)