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1- (5- chloro- 2- methyl- phenyl)- 3- (4- (5- trifluoromethyl- pyrazol- 1- yl)- phenyl)thiourea

antineoplastic; structure in first source

Also Known As:

AW00178

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - 1-(5-chloro-2-methyl-phenyl)-3-(4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl)thiourea: 1
Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Thiourea: 362
      - 1-(5-chloro-2-methyl-phenyl)-3-(4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl)thiourea: 1
- Sulfur Compounds: 278
  - Thiourea: 362
    - 1-(5-chloro-2-methyl-phenyl)-3-(4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl)thiourea: 1

Experts

1.	Hwang, Mi-Kyung: 1 article (06/2012)
2.	Kim, Seong Hwan: 1 article (06/2012)
3.	Lee, Kyunghee: 1 article (06/2012)
4.	Park, Mikyung: 1 article (06/2012)
5.	Ryu, Byung Jun: 1 article (06/2012)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 06/15/2012 - "In this study, we found that 1-(5-chloro-2-methyl-phenyl)-3-[4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl]-thiourea (AW00178) was able to sensitize TRAIL-resistant human lung cancer H1299 cells to TRAIL-mediated apoptosis. "
2.	Carcinoma (Carcinomatosis) 06/15/2012 - "Thiourea compound AW00178 sensitizes human H1299 lung carcinoma cells to TRAIL-mediated apoptosis."

Related Drugs and Biologics

1.	Thiourea