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22-thiocyanatosalvinorin A

structure in first source

Also Known As:

RB-64

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - Clerodane Diterpenes: 48
        22-thiocyanatosalvinorin A: 1

Experts

1.	DiBerto, Jeffrey F: 1 article (01/2015)
2.	Malanga, C J: 1 article (01/2015)
3.	Nichols, David E: 1 article (01/2015)
4.	Polepally, Prabhakar R: 1 article (01/2015)
5.	Robinson, J Elliott: 1 article (01/2015)
6.	Roth, Bryan L: 1 article (01/2015)
7.	White, Kate L: 1 article (01/2015)
8.	Zhu, Hu: 1 article (01/2015)
9.	Zjawiony, Jordan K: 1 article (01/2015)

Related Diseases

1.	Anhedonia 01/01/2015 - "Additionally, unlike unbiased KOR agonists, the G protein-biased ligand RB-64 does not induce sedation and does not have anhedonia-like actions, suggesting that a mechanism other than G protein signaling mediates these effects. "
2.	Ataxia (Dyssynergia) 01/01/2015 - "Here we provide data using a G protein-biased agonist, RB-64 (22-thiocyanatosalvinorin A), which suggests that KOR-mediated G protein signaling induces analgesia and aversion, whereas β-arrestin-2 signaling may be associated with motor incoordination. "

Related Drugs and Biologics

1.	GTP-Binding Proteins (G-Protein)
2.	Ligands

Related Therapies and Procedures

1.	Analgesia