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Lentiginosis Profusa

Also Known As:

Lentiginosis, Diffuse; Lentiginosis, Generalized; Lentiginosis, Inherited Patterned

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Pigmentation Disorders: 149
    - Hyperpigmentation: 3268
      - Melanosis: 1899
        Lentigo: 483
        Lentiginosis Profusa: 2

Related Diseases

1.	Dyskeratosis Congenita (X-Linked Dyskeratosis Congenita)
2.	Oculocutaneous Albinism (Albinism, Yellow Mutant)
3.	Waardenburg Syndrome (Klein Syndrome)
4.	Tuberous Sclerosis (Bourneville's Disease)
5.	Neurofibromatosis 1 (Neurofibromatosis Type I)

Experts

1.	Que, Syril Keena T: 1 article (03/2015)
2.	Ricketts, Janelle: 1 article (03/2015)
3.	Suchecki, Jeanine: 1 article (03/2015)
4.	Weston, Gillian: 1 article (03/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lentiginosis Profusa:

1.	Telomerase (Telomerase Reverse Transcriptase)IBA 03/01/2015 - "Oculocutaneous albinism, Menkes syndrome, tuberous sclerosis, neurofibromatosis type 1, dyskeratosis congenita, lentiginosis profusa syndrome, incontinentia pigmenti, and Waardenburg syndrome all are genodermatoses that have well established gene mutations affecting multiple biological pathways, including melanin synthesis, copper transport, cellular proliferation, telomerase function, apoptosis, and melanocyte biology. "
2.	Melanins (Melanin)IBA 03/01/2015 - "Oculocutaneous albinism, Menkes syndrome, tuberous sclerosis, neurofibromatosis type 1, dyskeratosis congenita, lentiginosis profusa syndrome, incontinentia pigmenti, and Waardenburg syndrome all are genodermatoses that have well established gene mutations affecting multiple biological pathways, including melanin synthesis, copper transport, cellular proliferation, telomerase function, apoptosis, and melanocyte biology. "
3.	Dihydroxyphenylalanine (Dopa)IBA 01/01/1975 - "Ionically separated epidermal sheets from pigmentations of two patients with lentiginosis profusa were incubated in dopa (3,4 dihydroxyphenylalanine) and slide-mounted. "
4.	CopperIBA 03/01/2015 - "Oculocutaneous albinism, Menkes syndrome, tuberous sclerosis, neurofibromatosis type 1, dyskeratosis congenita, lentiginosis profusa syndrome, incontinentia pigmenti, and Waardenburg syndrome all are genodermatoses that have well established gene mutations affecting multiple biological pathways, including melanin synthesis, copper transport, cellular proliferation, telomerase function, apoptosis, and melanocyte biology. "