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ent-7alpha-acetoxytrachyloban-18-oic acid

from Xylopia langsdorfiana; structure in first source

Also Known As:

trachylobane-360

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - ent-7alpha-acetoxytrachyloban-18-oic acid: 2

Experts

1.	Diniz, Margareth de Fátima Formiga Melo: 2 articles (11/2014 - 08/2012)
2.	Pita, João Carlos Lima Rodrigues: 2 articles (11/2014 - 08/2012)
3.	Tavares, Josean Fechine: 2 articles (11/2014 - 08/2012)
4.	da Silva, Marcelo Sobral: 2 articles (11/2014 - 08/2012)
5.	Dos Santos, Socrates Golzio: 1 article (11/2014)
6.	Gomes, Isis Fernandes: 1 article (11/2014)
7.	Sobral, Marianna Vieira: 1 article (11/2014)
8.	Castello-Branco, Marianna Vieira Sobral: 1 article (08/2012)
9.	Mangueira, Vivianne Mendes: 1 article (08/2012)
10.	Morelli, Sandra: 1 article (08/2012)

Related Diseases

1.	Sarcoma 180 11/01/2014 - "When administered intraperitoneally to mice, trachylobane-360 (T-360) significantly inhibits growth of the solid tumor sarcoma 180 transplanted in mice, without causing alterations in biochemical, hematological and histopathological parameters that are frequently associated with the clinical use of antineoplastic. " 08/10/2012 - "The in vivo inhibition rates of sarcoma 180 tumor development were 45.60, 71.99 and 80.06% at doses of 12.5 and 25 mg/kg of trachylobane-360 and 25 mg/kg of 5-FU, respectively. "
2.	Neoplasms (Cancer) 11/01/2014 - "When administered intraperitoneally to mice, trachylobane-360 (T-360) significantly inhibits growth of the solid tumor sarcoma 180 transplanted in mice, without causing alterations in biochemical, hematological and histopathological parameters that are frequently associated with the clinical use of antineoplastic. " 08/10/2012 - "The in vivo inhibition rates of sarcoma 180 tumor development were 45.60, 71.99 and 80.06% at doses of 12.5 and 25 mg/kg of trachylobane-360 and 25 mg/kg of 5-FU, respectively. "
3.	Leukopenia 08/10/2012 - "Leukopenia was observed after 5-FU treatment, but this effect was not seen with trachylobane-360 treatment. "

Related Drugs and Biologics

1.	Fluorouracil (Carac)
2.	Antineoplastic Agents (Antineoplastics)