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N- (4- ethylphenyl)- 2- ((4- ethyl- 5- (3- pyridinyl)- 4H- 1,2,4- triazol- 3- yl)thio)acetamide

an agonist of orphan receptor ion channel Orco; structure in first source

Also Known As:

VUAA1

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - Thioglycolates: 2
        N-(4-ethylphenyl)-2-((4-ethyl-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide: 2
- Sulfur Compounds: 278
  - Sulfhydryl Compounds: 4168
    - Thioglycolates: 2
      - N-(4-ethylphenyl)-2-((4-ethyl-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Triazoles: 1533
      - N-(4-ethylphenyl)-2-((4-ethyl-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide: 2

Experts

1.	Bernier, Ulrich R: 1 article (08/2021)
2.	Bloomquist, Jeffrey R: 1 article (08/2021)
3.	Demares, Fabien: 1 article (08/2021)
4.	Jiang, Shiyao: 1 article (08/2021)
5.	Norris, Edmund J: 1 article (08/2021)
6.	Yang, Liu: 1 article (08/2021)
7.	Jones, Patrick L: 1 article (01/2012)
8.	Pask, Gregory M: 1 article (01/2012)
9.	Reid, Paul R: 1 article (01/2012)
10.	Romaine, Ian M: 1 article (01/2012)

Related Diseases

1.	Malaria 01/01/2012 - "A search of our compound library identified several VUAA1 analogs that were selected for evaluation against HEK cells expressing Orco from the malaria vector Anopheles gambiae (AgOrco). "
2.	Bites and Stings (Sting) 08/01/2021 - "In repellency and bite protection screens, VUAA1 showed little activity against adult mosquitoes, apparently due to its low volatility, since its effectiveness was increased by heating or mixing with transfluthrin acid and citronella oil. "

Related Drugs and Biologics

1.	Acids
2.	transfluthrin
3.	citronella oil