Complement Factor I Deficiency

Also Known As:

C3 Inactivator Deficiency; C3G2 C3 glomerulopathy 2; Complement Component 3 Inactivator Deficiency

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Thrombotic Microangiopathies
2.	Inborn Genetic Diseases (Disease, Hereditary)
3.	Central Nervous System Vasculitis
4.	Vasculitis (Vasculitides)
5.	Multiple Sclerosis

Experts

1.	Ayadi, Imen: 1 article (03/2019)
2.	Cheour, Elhem: 1 article (03/2019)
3.	Dehman, Fatma: 1 article (03/2019)
4.	Gargah, Tahar: 1 article (03/2019)
5.	Gorgi, Yosr: 1 article (03/2019)
6.	Jallouli, Manel: 1 article (03/2019)
7.	Jlajla, Hend: 1 article (03/2019)
8.	Kallel Sellami, Maryam: 1 article (03/2019)
9.	Khedher, Rania: 1 article (03/2019)
10.	Laadhar, Lilia: 1 article (03/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Complement Factor I Deficiency:

1.	Fibrinogen (Factor I)FDA Link 03/01/2019 - "The aim of the present study was to characterize the molecular basis of complement factor I deficiency in Tunisian atypical haemolytic and uremic syndrome patients with low factor I levels. "
2.	Complement System Proteins (Complement)IBA 01/01/2023 - "Exploration of the complement system found a complement factor I deficiency whose activity normalized at the control carried out after 2 years. " 07/01/1997 - "Complement-activating ability of leucocytes from patients with complement factor I deficiency." 11/01/2023 - "Pearls & Oy-sters: Homozygous Complement Factor I Deficiency Presenting as Fulminant Relapsing Complement-Mediated CNS Vasculitis."
3.	chemotactic factor inactivatorIBA 11/01/2017 - "Early Versus Late Diagnosis of Complement Factor I Deficiency: Clinical Consequences Illustrated in Two Families with Novel Homozygous CFI Mutations." 10/01/2015 - "Novel CFI mutation in a patient with leukocytoclastic vasculitis may redefine the clinical spectrum of Complement Factor I deficiency." 12/01/2022 - "Complement factor I deficiency (CFID; OMIM #610984) is a rare immunodeficiency caused by deficiencies in the serine protease complement factor I (CFI). "
4.	Serine Proteases (Serine Protease)IBA 12/01/2022 - "Complement factor I deficiency (CFID; OMIM #610984) is a rare immunodeficiency caused by deficiencies in the serine protease complement factor I (CFI). "
5.	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 04/01/2022 - "Furthermore, other genetic disorders, such as complement factor I deficiency, phosphatidylinositol glycan anchor biosynthesis class T mutation, and neuronal intranuclear inclusion disease, can present as meningitis and encephalitis."
6.	Complement Factor I (C3b Inactivator)IBA 12/01/2022 - "Complement factor I deficiency (CFID; OMIM #610984) is a rare immunodeficiency caused by deficiencies in the serine protease complement factor I (CFI). "
7.	Interferon-betaIBA 01/01/2023 - "Thrombotic microangiopathy due to acquired complement factor I deficiency in a male receiving interferon-beta treatment for multiple sclerosis."
8.	ImmunosorbentsIBA 11/01/2001 - "First, we characterized the existence of a total complement factor I deficiency defined by undetectable levels by enzyme immunosorbent assay. "
9.	EnzymesIBA 11/01/2001 - "First, we characterized the existence of a total complement factor I deficiency defined by undetectable levels by enzyme immunosorbent assay. "
10.	Antigen-Antibody Complex (Immune Complex)IBA 01/01/2005 - "Here we report complement factor I deficiency in an 11-y-old girl from a consanguineous Turkish family, who presented with recurrent pyogenic infections, vasculitic eruptions and immune complex glomerulonephritis. " 01/01/2005 - "Complement factor I deficiency associated with recurrent infections, vasculitis and immune complex glomerulonephritis."