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zinc histidine dithiooctanamide

an antioxidant; structure in first source

Also Known As:

DHL-HisZn; sodium zinc histidine dithiooctanamide

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chen, Chao-Long: 2 articles (11/2017 - 12/2016)
2.	Goto, Shigeru: 2 articles (11/2017 - 12/2016)
3.	Hsu, Li-Wen: 2 articles (11/2017 - 12/2016)
4.	Lai, Chia-Yun: 2 articles (11/2017 - 12/2016)
5.	Nakano, Toshiaki: 2 articles (11/2017 - 12/2016)
6.	Inomata, Masafumi: 1 article (11/2017)
7.	Kitano, Seigo: 1 article (11/2017)
8.	Takaoka, Yuki: 1 article (11/2017)
9.	Chen, Chien-Chih: 1 article (12/2016)
10.	Chen, Kuang-Den: 1 article (12/2016)

Related Diseases

1.	Reperfusion Injury 05/15/2012 - "New α-lipoic acid derivative, DHL-HisZn, ameliorates renal ischemia-reperfusion injury in rats."
2.	Allergic Rhinitis 11/01/2017 - "Therapeutic potential of α-lipoic acid derivative, sodium zinc histidine dithiooctanamide, in a mouse model of allergic rhinitis." 11/01/2017 - "The therapeutic impact of DHL-HisZn on mast-cell-mediated type I hypersensitivity was evaluated by a mast-cell degranulation assay using bone marrow-derived mast cells and by a mouse model of ovalbumin (OVA)-induced allergic rhinitis. "
3.	Insulin Resistance 12/01/2016 - "Therefore, DHL-HisZn may have the capability to reduce insulin resistance." 12/01/2016 - "Our results indicate that DHL-HisZn enhances insulin sensitivity in adipocytes by increasing the expression of GLUT4 and IRS-1 via the activation of PPARγ and improving the antioxidant response during adipogenic differentiation. " 12/01/2016 - "Here, we investigated the effects of sodium zinc histidine dithiooctanamide (DHL-HisZn), a strong antioxidant, on PPARγ activation, adipocyte differentiation and insulin sensitivity. "
4.	Immediate Hypersensitivity 11/01/2017 - "The therapeutic impact of DHL-HisZn on mast-cell-mediated type I hypersensitivity was evaluated by a mast-cell degranulation assay using bone marrow-derived mast cells and by a mouse model of ovalbumin (OVA)-induced allergic rhinitis. "
5.	Hypersensitivity (Allergy) 11/01/2017 - "DHL-HisZn not only suppressed mast-cell degranulation but also ameliorated OVA-induced nasal hypersensitivity, with significant suppression of serum nitrate. "

Related Drugs and Biologics

1.	Thioctic Acid (Lipoic Acid)
2.	zinc histidine dithiooctanamide
3.	Ovalbumin
4.	Nitrates
5.	Antioxidants